Applications to patient care
â¢ Preconception counseling of obese and overweight women may be appropriate to discuss risks and to encourage weight loss and adoption of a healthy diet prior to pregnancy.
â¢ Maternal preconception lifestyle change and weight loss may also reduce the risk for preeclampsia and gestational/pregestational diabetes, which have also been associated with iatrogenic prematurity and an increased risk for ASD and other neurodevelopmental morbidity in offspring.
â¢ Evidence is insufficient to recommend routine omega-3 or omega-6 fatty acid supplementation in obese pregnant women to reduce the risk of offspring neurodevelopmental morbidity.
â¢ Evidence is insufficient to recommend routine use of metformin in obese pregnant women to reduce the risk of offspring neurodevelopmental morbidity.
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