Infertile reproductive-aged women with recurrent unilateral endometrioma had adverse outcomes from in vitro fertilization (IVF) compared with results in infertile reproductive-aged women with tubal factor infertility, according to a study in the journal Gynecological Endocrinology.
“A controversial issue is whether endometriosis per se exerts a detrimental effect on IVF outcomes,” wrote the Russian authors.
The purpose of the study was to assess the quality of embryos and the implantation rate in women with infertility associated with endometriosis. The 120 study patients, all ages 26 to 40, underwent IVF and intracytoplasmic sperm injection (ICSI).
They were then divided into two groups. Group One (n = 70, average age 33.21) consisted of patients with recurrent unilateral endometriomas, whereas Group Two (n = 50, average age 32.54) represented the control group with tubal factor infertility.
The quality of the retrieved embryos was evaluated according to the generally accepted classification of Gardner, indicating the rate of implantation in each group. Embryo transfer was performed for high-quality embryos.