Amanda Roman-Camargo, MD, discusses the prevalence of premature rupture of membrane (PROM) in the US and complications associated with it.

Each test is a single use disposable unit and cannot be reused.

The AmniSure ROM Test results are qualitative. Make no quantitative interpretation based on the test results.

When there is a significant presence of blood on the swab, the test can malfunction and is not recommended. In cases of only trace amounts of blood on the swab, the test still functions properly.

In very rare cases when a sample is taken 12 hours or later after a rupture, a false-negative result may occur due to obstruction of the rupture by fetus or resealing of the amniotic sac.

Test performance in patients without signs or symptoms of ROM is unknown.

Use results in conjunction with other clinical information.

Failure to detect membrane rupture does not assure the absence of membrane rupture.

Women may labor spontaneously despite a negative test result.

The performance of the AmniSure ROM Test has not been established in the presence of the following contaminants: anti-fungal creams or suppositories, K-Y® Jelly, Monistat Yeast Infection Treatment, Baby Powder (Starch and Talc), Replens Feminine Moisturizer, or Baby Oil. 

The performance of the AmniSure ROM Test has not been established in the presence of meconium in the amniotic fluid.

AmniSure ROM Test should be used as part of the overall clinical assessment

Prevalence and Complications of Preterm Rupture of Membrane

Vincenzo Berghella, MD, reviews the management and the etiology of preterm premature rupture of membranes (PPROM).

Management of Prelabor Rupture of Membrane

Experts in gynecology provide their perspective on the maternal and neonatal risks associated with the preterm premature rupture of membranes.

Risks Associated With Prelabor Rupture of Membrane

Gynecology experts review the March of Dimes (MOD) initiatives to keep the baby full-term and the ACOG guidelines for PPROM.

MOD Initiatives and ACOG Guidelines on PPROM

Amanda Roman-Camargo, MD, provides an overview on the various tests used for PPROM along with the risks for false results from these tests.

Available Tests to Diagnose PPROM 

Vincenzo Berghella, MD, reviews the noninvasive AmniSure test and its specificity and sensitivity in context to the traditional gold standard tests.

AmniSure: Noninvasive Test Using Biomarkers to Predict PPROM

Experts in gynecology anticipate using AmniSure as first line option in testing of PPROM and support use of newer biomarker-based testing in all hospitals.

Benefits of the AmniSure Test to Predict PPROM  

Advances in the Testing for Preterm Premature Rupture of Membrane

Experts provide an overview on the risks of preterm premature rupture of the amniotic membrane and the advances in diagnosing and testing for the rupture.