March 21st 2024
GlaxoSmithKline's phase 3 trial demonstrated promising overall and progression-free survival outcomes in patients with primary advanced or recurrent endometrial cancer, paving the way for potential FDA approval.
FDA panel recommends HPV DNA test as first-line cervical cancer screening
March 20th 2014In a unanimous vote, a Food and Drug Administration (FDA) advisory committee has recommended that the agency give premarket approval to a human papillomavirus (HPV) DNA test as first-line screening for cervical cancer.
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Oophorectomy cuts risk of cancer in BRCA1/2 carriers
March 6th 2014A study by Canadian researchers shows that preventive oophorectomy reduces risk of ovarian, fallopian tube, or peritoneal cancer by 80% in women who have BRCA1 or BRCA2 mutations. Published in The Journal of Clinical Oncology, the report also documented a 77% reduction in all-cause mortality.
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Monoclonal antibody increases cervical cancer survival
February 27th 2014Adding a monoclonal antibody (MAb)-bevacizumab-to combination chemotherapy may increase survival in patients with recurrent cervical cancer, according to results of a National Cancer Institute-funded randomized trial. Use of bevacizumab in cervical cancer is experimental; the MAb currently is approved to treat metastatic colorectal cancer, non-squamous, non-small cell lung cancer, and glioblastoma.
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Will an Aspirin a Day Keep Ovarian Cancer Away?
February 20th 2014Women who take aspirin daily may reduce their risk of ovarian cancer by 20%, new research has found. However, this preventive strategy isn't ready for prime time; additional study is needed before clinical recommendations can be made.
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‘Heat map’ of blood proteins may shed light on cervical cancer
January 16th 2014A small, preliminary study suggests that measurement of heat changes in blood proteins may have potential in detection and staging of cervical cancer. Published in PLoS One, the report describes what may be a unique plasma thermal profile for different disease stages that could help distinguish them from healthy tissue.
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2-stage screening promising for ovarian cancer
August 29th 2013A screening protocol that takes into consideration CA-125 levels over time and results of transvaginal ultrasound (TVS) shows promise in early detection of ovarian cancer, according to a new report from investigators at the University of Texas MD Anderson Cancer Center. In a large, prospective study, the combination demonstrated excellent specificity and positive predictive value (PPV) in a group of women at average risk of ovarian cancer.
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