Life Transitions

Low BMD linked to periodontitis in perimenopausal women

August 10, 2020

A prospective study of generally healthy perimenopausal women has concluded that low bone mineral density (BMD) is significantly linked with periodontal disease in women over 58 years old, and independent of tobacco consumption or oral hygiene.

Early menopause and cardiovascular disease

July 09, 2020

The authors noted that, although recent guidelines embrace using history of menopause before age 40 to refine atherosclerotic cardiovascular disease (ASCVD) risk assessments in middle-aged women, “robust data on cardio-vascular disease risk in this population is lacking.”

PD-L1 CNA as a biomarker in metastatic breast cancer

June 10, 2020

Australian researchers believe that PD-L1 may have potential as an indicator of potential response to chemotherapy in women with metastatic breast cancer. That was based on results of a randomized trial, presented at the European Society for Medical Oncology in Lugano, Switzerland.

Vasomotor symptoms and faster epigenetic aging

May 21, 2020

Accelerated biological aging was seen in women who had severe menopausal vasomotor symptoms (VMS) on enrollment in the Women’s Health Initiative Observational Study (WHI-OS), or late-occurring VMS (at enrollment but not at/during their reported menopause transition, according to a study in The Journal of Clinical Endocrinology & Metabolism.

Lessons learned from postmenopausal hormone therapy

May 12, 2020

The timing of postmenopausal hormone therapy (HT) significantly impacts coronary risk and overall benefit-to-risk profile, according to an overview of Women’s Health Initiative (WHI) results in the journal Menopause.