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Life Transitions
Fezolinetant making waves for VMS
July 26, 2022
Genevieve Neal-Perry, MD, PhD, sits down with Contemporary OB/GYN to discuss positive data from a recent phase 3 study evaluating fezolinetant (Astellas) for vasomotor symptoms (VMS).
PTSD significantly associated with cognitive decline in midlife women
July 05, 2022
Women with the highest PTSD symptoms level experienced significantly worse rates of change regarding learning and working memory.
Exposure to 'forever chemicals' linked to increased risk of hypertension
June 20, 2022
New research suggests cumulative exposure to PFAS could increase risk of incident hypertension by 71% among midlife women.
Hormone shift in menopause contributes to cardiovascular risk in aging women
May 18, 2022
New research from a team of investigators in Europe suggests hormonal changes during menopause could explain up to 10% of the increase in LDL-C associated with the transition to menopause among aging women
Calcium supplementation could increase risk of death in older adults with cardiovascular disease
May 09, 2022
An analysis of data from a Cleveland Clinic database indicates calcium supplementation in older adults with aortic stenosis was linked to an increased risk of mortality and worsening aortic stenosis.
NSAID use may reduce effectiveness of osteoporosis therapies
May 09, 2022
Data from a cohort of 5000 patients indicates that NSAID use may negatively affect clodronate therapy in older women.
Exposure to PFAS increases risk of diabetes in midlife women
April 15, 2022
Data from an analysis of a SWAN substudy suggests increased exposure to PFAS was linked to an increased risk of incident diabetes during midlife among women.
Endometriosis and early natural menopause
April 13, 2022
Women with laparoscopically confirmed endometriosis are at significantly higher risk for early natural menopause (ENM), and this risk was greater for nulliparous women and women who never reported using oral contraceptives, according to a study in JAMA Network Open.
Midlife overweight status linked to higher morbidity
March 24, 2022
A recent study found overweight status in midlife, compared to normal body mass index, was linked to a higher burden of morbidity and greater proportion of life lived with morbidity.
Fezolinetant demonstrates topline results in long-term phase 3 study for VMS
March 11, 2022
Astellas announced positive data from its study investigating the long-term safety of fezolinetant for the treatment of moderate to severe vasomotor symptoms (VMS) associated with menopause.