Noninvasive Prenatal Testing

January 13, 2022

Maneesh Jain, CEO and co-founder of Mirvie, a proprietary RNA platform that uses blood samples to predict pregnancy complications such as preeclampsia, sits down with Contemporary OB/GYN to discuss the potential of the test.

September 30, 2021

The 'routinization' of noninvasive prenatal testing (NIPT) and the increasing pressure to test and/or terminate affected pregnancies are 2 major ethical concerns of NIPT.

September 08, 2021

A study in the journal Ultrasound in Obstetrics & Gynecology1 has found that noninvasive prenatal testing (NIPT) can help in the early detection of a set of single gene disorders (SGDs), especially in the presence of either abnormal ultrasound findings or a family history.

August 31, 2021

Pregnant women do not believe that noninvasive prenatal testing (NIPT) is an obligation of responsible motherhood, according to a qualitative study that investigated the impact of NIPT on women's moral beliefs about the meaning of prenatal screening.

July 20, 2021

Clinicians should carefully consider using noninvasive prenatal testing (NIPT) for the screening of chromosomal abnormalities in twin pregnancies because the combined positive predictive value (PPV) is limited and the screening efficiency is not stable, according to a prospective study.

July 19, 2021

Despite the inadvisability of performing early amniocentesis (EA) before 15 gestational weeks due to a high rate of miscarriage, a retrospective cohort study has found no significant difference in the procedure-related risk of miscarriage between EA, at around 14 weeks gestation, and mid-trimester amniocentesis (MA).

June 21, 2021

A retrospective analysis has found that comprehensive examination of shallow-sequenced, whole-genome cell-free DNA (cfDNA) allows for the incidental detection of maternal tumors, with relatively high precision.

June 21, 2021

The association between confined placental mosaicism (CPM) and prenatal growth and adverse pregnancy outcomes is significant, according to a literature review in the journal Human Reproduction Update.

May 05, 2021

A systematic review and meta-analysis on the benefits of non-invasive prenatal testing (NIPT) for detecting hemolytic disease of fetus and newborn (HDNF) validates routing anti-D prophylaxis.

May 05, 2021

An analysis of a large cohort of patients who chose noninvasive prenatal testing (NIPT) as a screening method for fetal trisomy 21, 18, and 13 (T21, T18 and T13) and sex chromosome aneuploidies (SCA) concluded there were extremely high detection rates and exceptionally low false positive rates.