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Noninvasive Prenatal Testing
Fetal blood group genotype for managing hemolytic disease of fetus and newborn
May 05, 2021
A systematic review and meta-analysis on the benefits of non-invasive prenatal testing (NIPT) for detecting hemolytic disease of fetus and newborn (HDNF) validates routing anti-D prophylaxis.
Whole genome sequencing of cell-free DNA for NIPT
May 05, 2021
An analysis of a large cohort of patients who chose noninvasive prenatal testing (NIPT) as a screening method for fetal trisomy 21, 18, and 13 (T21, T18 and T13) and sex chromosome aneuploidies (SCA) concluded there were extremely high detection rates and exceptionally low false positive rates.
Economic impact of coverage expansion for NIPT
April 15, 2021
Expanding coverage for noninvasive prenatal testing (NIPT) through a performance-based, risk-sharing agreement (PBRSA) resulted in a significant increase in NIPT use, a significant decrease in conventional prenatal screening methods, and a negligible increase in per member per month (PMPM) cost at Harvard Pilgrim Health Care (HPHC) in New England.
Emotions about testing negative with NIPT
March 09, 2021
A small percentage of women whose noninvasive prenatal testing (NIPT) results were negative regretted taking the test and blamed themselves, according to a 1-year postpartum questionnaire survey.
Cost of cell-free DNA noninvasive testing for Down syndrome
March 09, 2021
A public health screening program for Down syndrome in Quebec, Canada, found that cell-free DNA noninvasive prenatal testing (NIPT) could be implemented at the same cost as the current screening program, according to computer simulations.
How insurance impacts access to NIPT
March 08, 2021
Some women are unable to choose noninvasive prenatal testing (NIPT), due to lack of insurance coverage, according to a pilot study in the Journal of Community Genetics.
Sonographic abnormalities in pregnancies after IVF
February 24, 2021
Preimplantation genetic testing for aneuploidy (PGT-A) is not associated with a difference in risk of fetal anomaly detected on mid-trimester anatomical survey, according to a study.
Expanding scope of noninvasive prenatal testing
February 23, 2021
“Our results can further inform the debate on the future uses of NIPT and future policy of its implementation,” said co-principal investigator Hazar Haidar, PhD, a lecturer in bioethics at Université du Québec à Montréal (UQAM), Montréal, Canada.
Noninvasive prenatal screening in twin pregnancies
February 02, 2021
The investigators found an extremely low failure rate of 0.31%.
Fetal aneuploidy screening with a noninvasive prenatal test
February 01, 2021
A population-based register study from the Netherlands has found that the percentage of pregnant women opting for fetal aneuploidy screening reached a high of 45.9% within 1 year after the introduction in 2017 of a noninvasive prenatal test (NIPT) as a first-tier test for all women.