ACOG noted that pregnant individuals faced increased risks of maternal morbidity and mortality from influenza, as well as fetal risks including congenital anomalies, spontaneous abortion, preterm birth, and low birth weight. The statement reported no evidence of adverse fetal effects from mRNA-derived vaccines, inactivated virus vaccines, bacterial vaccines, or toxoids and cited growing safety data supporting their use during pregnancy.
In addition to influenza, COVID-19, Tdap, and RSV vaccines, the statement addressed screening for hepatitis B using a triple panel screen in pregnant patients aged 18 years or older if not previously completed. Other vaccines could be recommended based on age, comorbidities, prior immunization status, or disease risk factors, with certain vaccines administered postpartum when indicated.
Addressing disparities and misinformation
The updated guidance also addressed disparities in vaccine uptake. ACOG reported that maternal vaccination rates remained suboptimal and that outbreaks of vaccine-preventable diseases were increasing. Barriers included misinformation and disinformation on social media, limited awareness of recommended vaccines, and a lack of trust in the medical system—particularly among communities of color affected by historical and ongoing systemic racism.
“Vaccine misinformation and disinformation is on the rise, and it’s unfortunately affecting people’s decisions about whether or not to get vaccinated and ultimately protect themselves and their pregnancies from preventable illness,” said Christopher M. Zahn, MD, FACOG, chief of clinical practice at ACOG.2
“The growing misinformation and disinformation and changing national recommendations are resulting in confusion for both patients and clinicians. It’s our duty at ACOG to ensure that ob-gyns and other clinicians who treat pregnant patients are equipped with evidence-based information to counsel their patients about which vaccines they need, and clinicians can find that essential information in this guidance,” added Zahn.
ACOG highlighted that studies consistently demonstrated higher vaccine acceptance when recommendations came directly from an obstetrician or obstetric care professional, with odds of acceptance 5-fold to 50-fold higher when clinicians both recommended and offered vaccination.1
Recommendations from the Committee Statement
Based on the principles from the Committee Statement, ACOG made the following recommendations:
- Obstetrician–gynecologists and other obstetric care professionals should routinely assess their pregnant patients' vaccination status.
- Obstetrician–gynecologists and other obstetric care professionals should recommend and, when possible, administer needed vaccines to their pregnant patients.
- Individuals who are or will be pregnant during the fall/winter respiratory illness season should receive annual influenza and coronavirus disease 2019 (COVID-19) vaccines.
- All pregnant individuals should receive a Tdap (tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis) vaccine during each pregnancy, as early in the 27–36 gestational-week window as possible.
- All eligible pregnant individuals who meet criteria should receive the respiratory syncytial virus (RSV) vaccine.
- Other vaccines may be recommended during pregnancy depending on the patient's age, prior immunizations, comorbidities, or disease risk factors.
References:
- Maternal Immunizations. Obstetrics & Gynecology ():10.1097/AOG.0000000000006230. February 18, 2026. Accessed February 18, 2026. doi:10.1097/AOG.0000000000006230
- ACOG releases updated guidance on maternal immunizations. American College of Obstetricians & Gynecologists. Published February 17, 2026. Accessed February 18, 2026. https://www.acog.org/news/news-releases/2026/02/acog-releases-updated-guidance-maternal-immunizations