Ampicillin remains poor choice for antepartum pyelonephritis
Antimicrobial susceptibility patterns of gram-negative rods causing antepartum pyelonephritis have shown little change over the last 15 years. Susceptibility patterns in 1992 to 1993 and 2004 to 2006 were similar, with 51% and 54% (respectively) of the Escherichia coli strains being resistant to ampicillin, according to Roberts and colleagues from Metrohealth Medical Center in Cleveland. However, E coli resistance to trimethoprim-sulfamethoxazole increased from 5% to 20%. No resistance to first-generation cephalosporins was reported. This study confirms that ampicillin is a poor choice for the treatment of antepartum pyelonephritis.
Antimicrobial susceptibility patterns of gram-negative rods causing antepartum pyelonephritis have shown little change over the last 15 years. Susceptibility patterns in 1992 to 1993 and 2004 to 2006 were similar, with 51% and 54% (respectively) of the Escherichia coli strains being resistant to ampicillin, according to Roberts and colleagues from Metrohealth Medical Center in Cleveland. However, E coli resistance to trimethoprim-sulfamethoxazole increased from 5% to 20%. No resistance to first-generation cephalosporins was reported. This study confirms that ampicillin is a poor choice for the treatment of antepartum pyelonephritis.
A Legacy of Excellence: Reflecting on the Final Print Edition of Contemporary OB/GYN
April 25th 2025Marking the end of an era and the beginning of a new chapter, the final print edition of Contemporary OB/GYN celebrates over 50 years of evidence-based guidance and unwavering support for clinicians.
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