A study recently published in BMJ Sexual & Reproductive Health has highlightedsafety and efficacy for early at-home medication abortion up to 12 weeks of pregnancy.1
In the trial, both women opting to induce early medical abortion at home and those opting to induce abortion surgically in the hospital achieved a completion rate of 97%. Investigators concluded this data supports expansion of early medical abortion to 12 weeks.1
Key takeaways
- A BMJ Sexual & Reproductive Health study found early at-home medication abortion up to 12 weeks’ gestation is 97% effective, matching in-hospital results.
- No significant differences were observed in incomplete abortion, ongoing pregnancy, or serious complication rates between home and hospital settings.
- Women undergoing at-home abortions were more likely to contact health care providers, mostly by phone, during the process.
- The World Health Organization supports at-home medical abortion up to 12 weeks, though some countries still limit access to 10 weeks.
- Telemedicine and Shield law provisions have become crucial for abortion access, particularly in states with near-total abortion bans.
“These findings are akin to those reported in studies of [early medical abortion] below 10 weeks’ gestation in both home and hospital settings. This demonstrates that [early medical abortion] at home between gestations of 10 and 12 weeks is highly effective and safe,” wrote investigators.1
Comparing at-home and in-hospital abortion outcomes
The retrospective review was conducted to compare the safety and efficacy of early medical abortion at home vs in a hospital setting after 10-weeks’ gestation.2 Abortions between 10- and 11-weeks 6 days’ gestation from April 2020 to March 2025 were included in the analysis.
Complete abortion rates were reported as the primary outcome, with secondary outcomes including rates of incomplete abortion, ongoing pregnancy, and serious complications. There were 371 early medication abortions included in the final analysis, 258 of which were performed at home and 113 in the hospital.2
Of these, 251 and 110, respectively, ended in complete abortion, highlighting a rate of 97% regardless of the setting for abortion. There were also no significant differences in incomplete abortion rates nor ongoing pregnancy rates, at 1.6% and 1.2%, respectively, at home, vs 2.6% and 0%, respectively, in the hospital.2
High efficacy across both settings
One case of hemorrhage needing transfusion and 3 cases of infection receiving intravenous antibiotics were reported, all in the at-home group. Overall, investigators concluded there is significant efficacy and safety for early medical abortion performed at home up to 12-weeks’ gestation, similar to when conducted in the hospital.2
Women performing early medication abortion at home were significantly more likely to have an unscheduled contact with a hospital gynecology department or abortion clinic, at 23% vs 9% those performing the procedure at home.1 However, the majority of contact in these patients was performed by telephone, with a rate of 11% vs 4% of the hospital group.
Rates of requiring a return visit to the abortion clinic were 7% and 2%, respectively. Investigators noted the increased rate of contacting professionals in the at-home abortion group may be explained by greater contact with a health care professional during the procedure in the hospital group.
Expanding access
The accessibility of at-home medication abortion was significantly expanded during the COVID-19 pandemic when legislation permitted women to take the drugs mifepristone and misoprostol outside of a hospital setting.
According to the World Health Organization, these drugs can be taken up to 12-weeks’ gestation. Despite this recommendation, countries such as England and Wales limit the use of at-home medication abortion to 10-weeks’ gestation.1
“In line with WHO guidance, action is needed to extend [early medical abortion] at home up to 11+6 [12] weeks to women across the rest of the UK and beyond,” wrote investigators.1
Telemedicine as a lifeline for abortion access
The importance of remote contact availability for medication abortion has been highlighted by Angel Foster, MD, founder of The Massachusetts Abortion Access Project, in an interview with Contemporary OB/GYN.3 According to Foster, approximately 1 in 3 women live in states with near-total abortion bans or first-trimester restrictions, leading to increased anxiety.
In the wake of these changes, 1 in 4 abortions nationwide are performed through telehealth. According to Foster, this method is highly acceptable to patients, providing an alternative to potentially long travel distances to brick-and-mortar clinics.3
“Almost all the abortions that are taking place in states with near-total bans are taking place through Shield law provisions and through telemedicine, and so we know that this is a lifeline for a lot of people,” said Foster.3
References
- Early medical abortion at home up to 12 weeks is safe, effective, and comparable to hospital care. BMJ Group. October 2, 2025. Accessed October 8, 2025. https://www.eurekalert.org/news-releases/1100339.
- Quinn J, Reynolds-Wright JJ, McCabe K, et al. Safety and efficacy of early medical abortion at home between 10+0 and 11+6 weeks' gestation: a retrospective review. BMJ Sexual & Reproductive Health. 2025. doi:10.1136/bmjsrh-2025-202947
- Foster A. Angel Foster, MD, highlights the importance of telehealth for abortion care. Contemporary OB/GYN. July 30, 2025. Accessed October 8, 2025. https://www.contemporaryobgyn.net/view/angel-foster-md-highlights-the-importance-of-telehealth-for-abortion-care.
