Breastfeeding lowers risk of rheumatoid arthritis

Article

Women who breastfeed their infants for 13 months or longer are less likely to develop rheumatoid arthritis, according to an article published online May 13 in the Annals of the Rheumatic Diseases.

Women who breastfeed their infants for 13 months or longer are less likely to develop rheumatoid arthritis, according to an article published online May 13 in the Annals of the Rheumatic Diseases.

Mitra Pikwer, of Malmo University Hospital in Malmo, Sweden, and colleagues investigated whether breastfeeding and oral contraceptives affected the future risk of rheumatoid arthritis in a community-based cohort of 18,326 Swedish women. Lifestyle factors obtained from self-administered questionnaires were compared in 136 women with rheumatoid arthritis and 544 age-matched controls.

Prolonged breastfeeding was associated with a reduced risk of rheumatoid arthritis, the investigators found. Compared to women who did not breastfeed, the odds ratio was 0.46 for women who breastfed for at least 13 months and 0.74 for women who breastfed for between 1 and 12 months. The protective effect of prolonged breast-feeding remained significant after controlling for smoking and educational level, the report indicates. Oral contraceptives did not impact risk, the researchers note.

"Possible explanations for the protective effect of breastfeeding include long-term immunomodulation, such as the development of progesterone receptors on lymphocytes, dysregulated hypothalamic-pituitary-adrenal access, and differences in cortisol concentrations," the authors write.

Pikwer M, Bergström U, Nilsson JA, et al. Breast-feeding, but not oral contraceptives, is associated with a reduced risk of rheumatoid arthritis. Ann Rheum Dis. Published Online First: 14 May 2008. doi:10.1136/ard.2007.084707.

Recent Videos
The significance of the Supreme Court upholding mifepristone access | Image Credit: unchealth.org
One year out: Fezolinetant displays patient satisfaction for managing hot flashes | Image Credit: sutterhealth.org
Addressing maternal health inequities: Insights from CDC's Wanda Barfield | Image Credit: cdc.gov
Addressing racial and ethnic disparities in brachial plexus birth Injury | Image Credit: shrinerschildrens.org
Innovations in prenatal care: Insights from ACOG 2024 | Image Credit:  uofmhealth.org.
Unlocking therapeutic strategies for menopausal cognitive decline | Image Credit: uclahealth.org.
Navigating menopause care: Expert insights from ACOG 2024 | Image Credit: mayo.edu.
raanan meyer, md
© 2024 MJH Life Sciences

All rights reserved.