Results from the study showed antitumor activity and safety to be similar to olaparib and durvalumab monotherapy outcomes.
New findings from a MEDIOLA trial found that the combination of Olaparib and durvalumab in treating germline BRCA1-mutated or BRCA2-mutated metastatic breast cancer had similar results to those previously observed in monotherapy studies of both Olaparib and durvalumab.
The study’s authors noted the promising antitumor activity and safety of this combination therapy but call for further research via a randomized controlled trial to determine therapeutic and long-term clinical benefits.
For further details on the study and its findings, visit Drug Topics.
Exogenous hormones and patients at increased risk for breast cancer
October 17th 2023This lecture, presented by Holly J. Pederson, MD, at The Menopause Society 2023 Annual Meeting, looked at combined oral contraceptives in BRCA carriers and other high-risk patients, and hormone therapy in postmenopausal gene carriers as well as other high-risk women.
Read More
Hormone replacement therapy does not increase breast cancer recurrence, mortality in survivors
July 20th 2022An analysis of data from more than 8400 postmenopausal women with a history of early-stage nonmetastatic, ER-positive breast cancer suggests there was no increase in risk of breast cancer recurrence or mortality observed with use of vaginal estrogen therapy or menopausal hormone therapy.
Read More