Using a cervical stitch to prevent singleton pregnancy loss may or may not work. In a recent British meta-analysis, which included seven trials and just over 2,000 women, although the results suggested that cerclage might reduce the risk of pregnancy loss or death of the baby before hospital discharge by 19%, the percentage failed to reach statistical significance (OR 0.81; 95% CI, 0.60-1.10). And efficacy seemed uninfluenced by indication, maternal obstetric history, cervical length, or timing of the procedure during pregnancy.
Using a cervical stitch to prevent singleton pregnancy loss may or may not work. In a recent British meta-analysis, which included seven trials and just over 2,000 women, although the results suggested that cerclage might reduce the risk of pregnancy loss or death of the baby before hospital discharge by 19%, the percentage failed to reach statistical significance (OR 0.81; 95% CI, 0.60-1.10). And efficacy seemed uninfluenced by indication, maternal obstetric history, cervical length, or timing of the procedure during pregnancy.
The analysis also showed that the procedure should not be used for pregnancies with multiple gestations. In this group, according to the data, cerclage has a detrimental effect on the outcome of pregnancy loss or death before discharge from the hospital (OR 5.88; 95% CI, 1.14-30.19), but only a small number of multiple pregnancies were included in the analysis.
Jorgensen AL, Alfirevic Z, Tudor Smith CT, et al. Cervical stitch for preventing pregnancy loss: individual patient data meta-analysis. BJOG. 2007;114:1460-1476.
SART data indicates rise in IVF use in 2022
April 24th 2024Dive into the latest statistics from the Society for Assisted Reproductive Technology, revealing a 6% increase in in vitro fertilization cycles and a surge in egg freezing, amidst a landscape of rising fertility service demand and evolving clinical practices.
Read More
Hormone therapy safety: Study finds potential benefits for senior women
April 24th 2024A recent large-scale study challenged age-related concerns, suggesting hormone therapy may offer safety and even benefits for menopausal women aged over 65 years, aligning with The Menopause Society's 2022 Position Statement.
Read More