Researchers reviewed data on women exposed to an HPV vaccine up to 1 month prior to onset of their last menstrual period or at any time during pregnancy.
Researchers reviewed prospective data on 517 women from the United States, France, and Canada who were exposed to the human papillomavirus (HPV) type 6/11/16/18 vaccine up to 1 month before the onset of their last menstrual period or at any time during pregnancy.
Of these women, 451 had live births, including 3 sets of twins, for a total of 454 neonates. Overall rates of spontaneous abortion, major birth defects, and fetal death were 6.9 per 100 outcomes (95% confidence interval [CI], 4.8-9.6), 2.2 per 100 liveborn neonates (95% CI, 1.05-4.05), and 1.5 per 100 outcomes (95% CI, 0.60-3.09), respectively. All of the rates were no greater than those in unexposed populations.
Dana A, Buchanan K, Goss MA, et al. Pregnancy outcomes from the pregnancy registry of a human papillomavirus type 6/11/16/18 vaccine. Obstet Gynecol. 2009;114(6):1170-1178.
A Legacy of Excellence: Reflecting on the Final Print Edition of Contemporary OB/GYN
April 25th 2025Marking the end of an era and the beginning of a new chapter, the final print edition of Contemporary OB/GYN celebrates over 50 years of evidence-based guidance and unwavering support for clinicians.
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