Menorrhagia nonhormonal treatment gets FDA nod

Article

After a priority review, the US Food and Drug Administration has approved Xanodyne Pharmaceuticals' formulation of tranexamic acid tablets (Lysteda) for the treatment of cyclic menorrhagia.

After a priority review, the US Food and Drug Administration has approved Xanodyne Pharmaceuticals' formulation of tranexamic acid tablets (Lysteda) for the treatment of cyclic menorrhagia. The nonhormonal product works by stabilizing a protein essential to clotting, thus reducing excessive clot breakdown in the uterus.

Approximately 10% of women of reproductive age in the United States report regular intervals of menstruation, with volume that may exceed 80 mL per cycle.

Commonly reported adverse effects of tranexamic acid tablets may include headache; sinus and nasal symptoms; pain in the back, abdomen, muscles, or joints; muscle cramps; anemia; and fatigue. Women who use oral contraceptives concurrently with tranexamic acid tablets have increased risk of blood clots, heart attack, or stroke.

US Food and Drug Administration. FDA approves Lysteda to treat heavy menstrual bleeding [press release]. November 13, 2009. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm190551.htm. Accessed November 20, 2009.

Recent Videos
Devon Ramaeker, MD
Elizabeth Gandee, APRN-CNP, highlights gaps in women's menopause knowledge | Image Credit: wexnermedical.osu.edu
Doula highlights how postpartum care is failing new mothers | Image Credit: linkedin.com
Nicky Herrick MD; and Anushree Agarwal, MD, MBBS, highlight their study on cardiac arrhythmias in pregnancy | Image Credit: © Igor Borodin - stock.adobe.com.
Lisa Becht, MD, FACOG, sheds light on fertility awareness | Image Credit: havingbabies.com.
First US national HPV conference highlights advances in cancer prevention | Image Credit: uchealth.com.
Mitchell Creinin, MD, reports estetrol pill eases menstrual symptoms | Image Credit: health.ucdavis.edu
1 expert is featured in this series.
Susanna Mitro, PhD, reveals ethnic disparities in uterine fibroid diagnosis | Image Credit: divisionofresearch.kaiserpermanente.org.
Shayna Mancuso, DO, highlights the real impact of menopause | Image Credit: linkedin.com.
Related Content
© 2025 MJH Life Sciences

All rights reserved.