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17-alpha hydroxyprogesterone (17P) may reduce preterm deliveries, but it doesn't seem to reduce perinatal deaths. At least that's the conclusion of a large study reported at this year's Annual Clinical Meeting. To reach that conclusion, University of Miami investigators examined a database of high-risk patients with prior preterm deliveries (PTD) (n=699) and current singleton gestations who had been receiving weekly 250 mg IM injections of 17P, or observation (n=880). While those on progesterone delivered at 36.2 weeks (+/- 4.2), compared to 35.5 weeks ( +/- 4.2) (P<0.001), there were no significant differences between the groups when researchers looked at the incidence of stillbirths, neonatal deaths, miscarriages at less than 24 weeks, or total perinatal deaths.
Gonzalez-Quentero VH, Smarkusky L, Carter J, et al. 17-alpha-hydroxyprogesterone caproate: perinatal mortality and pregnancy outcomes. Obstet Gynecol. 2007;109(suppl):7S.
Removing parental consent reduces delays in adolescent abortion care
February 12th 2025A new study links the removal of parental consent requirements for abortion in Massachusetts to significantly earlier gestational age at the time of the procedure, highlighting the impact of reduced barriers on timely reproductive care.
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