News: Comparing osteoporosis drugs

Article

Seems little difference exists in available osteoporosis drugs when it comes to nonvertebral fractures.

It seems little difference exists in available osteoporosis drugs when it comes to prevention of nonvertebral fractures.

A recent cohort study involving over 43,000 new recipients of oral bisphosphonates, nasal calcitonin, and raloxifene who began treatment between the years 2000 and 2005 found that differences in the risk of fracture of the hip, humerus, radius, or ulna between risedronate or raloxifene and alendronate are small, and that women taking nasal calcitonin may be at higher risk for nonvertebral fractures than women taking alendronate.

The authors calculated hazard ratios (HR) for risedronate and raloxifene of 1.01 and 1.18, respectively. Among women with a previous fracture, those taking raloxifene experienced more nonvertebral fractures within 12 months (HR 1.78; CI, 1.20–2.63) than those taking alendronate. Women taking calcitonin were at about 40% higher risk for nonvertebral fractures than those taking alendronate (HR 1.40; CI, 1.20–1.63), but the authors concluded that additional studies that can better adjust for potential confounding are necessary to confirm these results.

Recent Videos
First US national HPV conference highlights advances in cancer prevention | Image Credit: uchealth.com.
Mitchell Creinin, MD, reports estetrol pill eases menstrual symptoms | Image Credit: health.ucdavis.edu
1 expert is featured in this series.
Susanna Mitro, PhD, reveals ethnic disparities in uterine fibroid diagnosis | Image Credit: divisionofresearch.kaiserpermanente.org.
Shayna Mancuso, DO, highlights the real impact of menopause | Image Credit: linkedin.com.
Jihong Liu, ScD, explains how to improve perinatal outcomes in COVID patients | Image Credit: sc.edu.
1 expert is featured in this series.
Jihong Liu, ScD, highlights adverse perinatal outcomes linked to the COVID pandemic | Image Credit: sc.edu.
Experts highlight infant health benefits from minor diet changes in pregnancy | Image Credit: ohsu.edu.
Connie Stark, RNC, PNC, provides fertility preservation insights for endometriosis patients | Image Credit: linkedin.com.
Related Content
© 2025 MJH Life Sciences

All rights reserved.