News: Meconium markers may point to fetal alcohol risks

Article

Fatty acid ethyl esters in meconium may identify infants who are at risk of mental and psychomotor developmental delays due to fetal alcohol exposure.

Fatty acid ethyl esters in meconium may identify infants who are at risk of mental and psychomotor developmental delays due to fetal alcohol exposure, according to research released online in advance of publication in the Journal of Pediatrics.

Jennifer Peterson, MD, of the Case Western Reserve University School of Medicine in Cleveland, and colleagues analyzed data from 190 infants. Meconium samples were taken shortly after birth, and mothers answered questions on their alcohol use during pregnancy within a month of the delivery. Mothers were predominantly black and of low socioeconomic status. The researchers assessed infants' neurodevelopment at 6.5 months, 1 year, and 2 years of age, using the Bayley Scales of Infant Development.

Higher concentrations of fatty acid ethyl esters (FAEE)-which are nonoxidative metabolites of ethanol-were significantly associated with poorer mental and psychomotor development at all of the follow-up visits. The FAEE, in particular, were ethyl myristate, ethyl palmitate, ethyl oleate, ethyl linoleate, ethyl linolenate, and ethyl arachidonate.

Peterson J, Kirchner HL, Xue W, et al. Fatty Acid Ethyl Esters in Meconium are Associated with Poorer Neurodevelopmental Outcomes to Two Years of Age. J Ped. 2008. doi:10.1016/j.jpeds.2007.11.009.

Related Videos
Why doxycycline PEP lacks clinical data for STI prevention in women
The importance of nipocalimab’s FTD against FNAIT | Image Credit:  linkedin.com
Enhancing cervical cancer management with dual stain | Image Credit: linkedin.com
Fertility treatment challenges for Muslim women during fasting holidays | Image Credit: rmanetwork.com
Understanding the impact of STIs on young adults | Image Credit: providers.ucsd.edu.
CDC estimates of maternal mortality found overestimated | Image Credit: rwjms.rutgers.edu.
Study unveils maternal mortality tracking trends | Image Credit: obhg.com
How Harmonia Healthcare is revolutionizing hyperemesis gravidarum care | Image Credit: hyperemesis.org
Unveiling gender disparities in medicine | Image Credit:  findcare.ahn.org.
Exploring the intersection of heart health and women's health | Image Credit: cedars-sinai.org
Related Content
© 2024 MJH Life Sciences

All rights reserved.