Including Gram's stain screening for asymptomatic vaginal infection in an early second-trimester routine prenatal visit can reduce the rate of preterm delivery by about 44%, according to the results of a recent prospective, randomized, controlled trial conducted in Austria.
Including Gram's stain screening for asymptomatic vaginal infection in an early second-trimester routine prenatal visit can reduce the rate of preterm delivery by about 44%, according to the results of a recent prospective, randomized, controlled trial conducted in Austria.
Researchers included over 4,000 pregnant women presenting to non-hospital-based antenatal clinics for routine prenatal visits. They provided the results of the vaginal smears for women in the intervention group to their caregivers, who, in turn, provided standard treatment and follow-up for any detected infections. That included oral or topical clindamycin for bacterial vaginosis, local clotrimazole for candidiasis, and topical metronidazole for trichomoniasis. The researchers did not provide test results, however, to caregivers of women in the control group.
The rate of preterm births (less than 37 weeks) was 3% in the intervention group versus 5.3% in the control group (95% confidence interval 1.2 to 3.6; P=0.0001). The rate of preterm infants with a birthweight of 2,500 g or less in the intervention group was half (1.7%) that in the control group (3.5%) (P= 0.0002). The rate of late miscarriage was also reduced by 50%.
Unraveling preeclampsia: Insights into heterogeneity and intravascular inflammation
April 22nd 2024A recent study delved into the intricate clusters of term preeclampsia, shedding light on its diverse manifestations and the pivotal role of intravascular inflammation, paving the way for improved classification and management strategies.
Read More
Personalized opioid protocol for cesarean deliveries: Reduced prescriptions reported
April 19th 2024A recent suggests that implementing a personalized opioid prescription protocol significantly reduces total morphine milligram equivalents and the number of opioid tablets prescribed at discharge following cesarean delivery.
Read More
Long-term mortality risks for women with adverse pregnancy outcomes
April 19th 2024A recent study revealed that women who experience major adverse pregnancy outcomes face heightened long-term mortality risks, shedding light on the need for comprehensive understanding and preventative measures in women's health.
Read More