Vaginally applied progesterone gel provides higher endometrial levels and lower systemic levels of progesterone than intramuscularly administered progesterone, according to a prospective, randomized study involving 32 postmenopausal women. All of the participants used transdermal estradiol (50 ?g/day, a patch each week) for 2 weeks. In addition, they used 50 mg of either vaginal progesterone gel or IM progesterone in oil after 24 hours to oppose the transdermal estradiol.
Maternal hypertension and diabetes linked to worse offspring cardiovascular health
February 17th 2025A new study finds that children born to mothers with hypertensive disorders of pregnancy or gestational diabetes are at a higher risk of developing cardiovascular health issues by ages 10 to 14 years.
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