Vaginal progesterone gel may be preferable for luteal phase support
Vaginally applied progesterone gel provides higher endometrial levels and lower systemic levels of progesterone than intramuscularly administered progesterone, according to a prospective, randomized study involving 32 postmenopausal women. All of the participants used transdermal estradiol (50 ?g/day, a patch each week) for 2 weeks. In addition, they used 50 mg of either vaginal progesterone gel or IM progesterone in oil after 24 hours to oppose the transdermal estradiol.
SKYLIGHT trials confirm safety and efficacy of fezolinetant against sleep disturbances
September 13th 2024At the 2024 Annual Meeting of The Menopause Society, the positive safety and efficacy data of fezolinetant against sleep disturbances from the SKYLIGHT 1 and 2 trials was presented.
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