SPOTLIGHT -
Pregnant women with severe mental illness benefit from continued antidepressant use
There was a lower probability of initiating psycholeptics and having postpartum psychiatric emergencies in the early discontinuer and late discontinuer groups compared to the continuers.
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New Predictors for hepatitis B vaccine response in IBD patients
Individuals that did not respond had a lower percentage of naïve T cells compared to responders, while responders had a lower percentage of Th2 and CD4 central memory subsets before vaccination.
Offspring of mothers With primary immunodeficiencies at an increased risk of psychiatric disorders
The same risk was not found for offspring of fathers with primary immunodeficiencies.
Low-molecular-weight heparin non-superior to standard therapy in reducing miscarriages
The most common thrombophilia types were heterozygosity for factor V Leiden, prothrombin 20210A mutation, and protein S deficiency.
Young motherhood, child ADHD link explained
The strongest confounders were family income, caregiver education, and ADHD polygenic risk scores for ADHD clinical range diagnoses.
HBsAg-positive status, excessive gestational weight gain risk factors for gestational diabetes mellitus
HBsAg-positive women with adequate gestational weight again among pre-pregnancy normal-weight women had a higher risk of gestational diabetes mellitus than HBs-Ag-negative women.
Allopurinol use linked to lower risk of first-ever coronary event
Exposure to more than 100 mg was linked to significantly lower odds ratios for first-ever ACS event for women.
Glucocorticoid use results in BMD loss for women with rheumatic disease
Anti-osteoporotic treatment resulted in increased BMD to a greater extent in patients treated with less than 5 mg per day of prednisone.
Higher hepatitis viral load increases risk of vertical transmission
Among pregnant women coinfected with HIV, a higher hepatitis C viral load increased the likelihood of transmitting HCV to children.
Prenatal exposure to endocrine-disrupting chemicals increases risk of liver injury
There was an increased odds of liver injury per exposure-mixture quartile increase for organochlorine pesticides, PBDEs) perfluoroalkyl substances, and metals.
Study: Link between early sleep disturbances and later behavioral problems
Researchers highlight the need for early interventions.