C-reactive protein probably can't predict chorioamnionitis

Article

S

No clear evidence exists to support the use of C-reactive protein (CRP) for the early diagnosis of chorioamnionitis following preterm prelabor rupture of membranes, according to a systematic review from the United Kingdom.

Researchers reviewed eight studies including 610 cases and found wide variation in the results. Three of the studies concluded that CRP was diagnostically useful, although one suggested using a higher CRP threshold (30, 35, or 40 mg/L for single estimations or >20 mg/L for serial estimations), while the remaining studies concluded that CRP as a diagnostic tool for chorioamnionitis was poor.

Part of the problem is the disagreement about what CRP values are normal during pregnancy and whether concentrations should increase as pregnancy progresses. While the use of serial measurements of CRP seems promising, it requires further investigation.

Recent Videos
The significance of the Supreme Court upholding mifepristone access | Image Credit: unchealth.org
One year out: Fezolinetant displays patient satisfaction for managing hot flashes | Image Credit: sutterhealth.org
Addressing maternal health inequities: Insights from CDC's Wanda Barfield | Image Credit: cdc.gov
Addressing racial and ethnic disparities in brachial plexus birth Injury | Image Credit: shrinerschildrens.org
Innovations in prenatal care: Insights from ACOG 2024 | Image Credit:  uofmhealth.org.
Unlocking therapeutic strategies for menopausal cognitive decline | Image Credit: uclahealth.org.
Navigating menopause care: Expert insights from ACOG 2024 | Image Credit: mayo.edu.
raanan meyer, md
© 2024 MJH Life Sciences

All rights reserved.