Cover Story: Repeat antenatal corticosteroids: A time for caution

While a single course of antenatal corticosteroids improves neonatal outcomes among infants born prematurely, the efficacy and safety of repetitive courses of ACS (including rescue dosing) is less clear. In the absence of adequate data to support a policy of repetitive dosing of ACS, such therapy should only be used as part of well-designed clinical trials.