FDA approves new thrombin clotting solution for surgery

Article

The Food and Drug Administration recently announced that it has approved a clotting solution made using recombinant DNA techniques, called Recothrom, to help stop bleeding of small blood vessels during surgery. In addition, the FDA has expanded the indication of Evicel-a liquid fibrin sealant previously approved for liver and vascular surgeries-to include its use during general surgery.

The Food and Drug Administration recently announced that it has approved a clotting solution made using recombinant DNA techniques, called Recothrom, to help stop bleeding of small blood vessels during surgery. In addition, the FDA has expanded the indication of Evicel-a liquid fibrin sealant previously approved for liver and vascular surgeries-to include its use during general surgery.

Recothrom is a topical thrombin solution that surgeons can apply to reduce bleeding from capillaries and other small blood vessels during surgery when other techniques to stop blood loss fail. The recombinant thrombin in the solution is produced from Chinese hamster ovary cells that have been genetically modified to produce human thrombin. Recothrom is manufactured by ZymoGenetics, Inc., of Seattle.

Evicel, a liquid fibrin sealant, is applied during surgery to small oozing blood vessels, and helps to form a covering to stop bleeding. The sealant contains fibrinogen and thrombin, two proteins that promote the formation of fibrin. Evicel is produced by OMRIX biopharmaceuticals LTD, Kiryat Ono, Israel.

News Release, January 27, 2008: FDA Approves First Clotting Solution Made Using Recombinant DNA Technology. Available at http://www.fda.gov/bbs/topics/NEWS/2008/NEW01779.html.

Related Videos
Why doxycycline PEP lacks clinical data for STI prevention in women
The importance of nipocalimab’s FTD against FNAIT | Image Credit:  linkedin.com
Enhancing cervical cancer management with dual stain | Image Credit: linkedin.com
Fertility treatment challenges for Muslim women during fasting holidays | Image Credit: rmanetwork.com
Understanding the impact of STIs on young adults | Image Credit: providers.ucsd.edu.
CDC estimates of maternal mortality found overestimated | Image Credit: rwjms.rutgers.edu.
Study unveils maternal mortality tracking trends | Image Credit: obhg.com
How Harmonia Healthcare is revolutionizing hyperemesis gravidarum care | Image Credit: hyperemesis.org
Unveiling gender disparities in medicine | Image Credit:  findcare.ahn.org.
Exploring the intersection of heart health and women's health | Image Credit: cedars-sinai.org
Related Content
© 2024 MJH Life Sciences

All rights reserved.