Fetal Fibronectin: The Benefits of a High Negative Predictive Value in Management of Preterm Labor

September 15, 2017
Brigid McCue, MD, PhD

Dr. McCue is Chief, Ob/Gyn and Midwifery, Beth Israel Deaconess Hospital-Plymouth, Plymouth, Massachusetts.

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Vanessa E. Torbenson, MD, FACOG

The clinical diagnosis of preterm labor (PTL) has up to a 50% false-positive rate, often leading to unnecessary hospitalizations and interventions. What objective tools can clinicians use to accurately diagnose true PTL - and reduce the drain on resources and overexposure to treatments?

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The clinical diagnosis of preterm labor (PTL) has up to a 50% false-positive rate, often leading to unnecessary hospitalizations and interventions. What objective tools can clinicians use to accurately diagnose true PTL - and reduce the drain on resources and overexposure to treatments?

This supplement discusses considerations and strategies for assessing PTL that include:

  • The role of diagnostic testing for fetal fibronectin (fFN) in the work up of women with symptoms of PTL
  • The importance of combining fFN values with cervical length measurement
  • Evidence-based protocols for the evaluation of PTL
  • A summary of evidence verifying the cost savings associated with the evaluation protocol

Read the supplement now to learn more about the management of PTL.

Download Supplement