New imaging approach accurately predicts breast Cancer recurrence

Article

A high-resolution imaging method can accurately predict the risk of tumor recurrence in women.

A high-resolution imaging method can accurately predict the risk of tumor recurrence in women with invasive breast cancer, researchers report in the July issue of Radiology.

Ka-Loh Li, PhD, from the University of California San Francisco, and colleagues retrospectively reviewed high-spatial-resolution signal enhancement ratio (SER) gadolinium-enhanced magnetic resonance images acquired with a three time point high-resolution method from 48 women who underwent neoadjuvant therapy for invasive breast cancers from 1995 to 2002.

The researchers found that disease recurrence was strongly predicted by breast tumor volume and the volume of cancerous breast tissue infiltrating into the parenchyma. Of the 20 patients with recurrence, 75% were identified as having a high risk of recurrence and all nine patients who died were identified as having a 100% risk of recurrence. None of the patients without recurrence were misidentified as being at high risk of recurrence. Of the three prechemotherapy variables (total tumor volume, tumor volumes with high, and low SER), only the low SER and high SER tumor volumes were significant and independent predictors of recurrence.
“High-spatial-resolution SER imaging may improve prediction for patients at high risk for disease recurrence and death,” Li and colleagues conclude.

Li KL, Partridge SC, Joe BN, et al. Invasive breast cancer: predicting disease recurrence by using high-spatial-resolution signal enhancement ratio imaging. Radiology. 2008;248:79-87.

Recent Videos
The significance of the Supreme Court upholding mifepristone access | Image Credit: unchealth.org
One year out: Fezolinetant displays patient satisfaction for managing hot flashes | Image Credit: sutterhealth.org
Addressing maternal health inequities: Insights from CDC's Wanda Barfield | Image Credit: cdc.gov
Addressing racial and ethnic disparities in brachial plexus birth Injury | Image Credit: shrinerschildrens.org
Innovations in prenatal care: Insights from ACOG 2024 | Image Credit:  uofmhealth.org.
Unlocking therapeutic strategies for menopausal cognitive decline | Image Credit: uclahealth.org.
Navigating menopause care: Expert insights from ACOG 2024 | Image Credit: mayo.edu.
raanan meyer, md
© 2024 MJH Life Sciences

All rights reserved.