News: Probiotics prevent necrotizing enterocolitis in preemies

Article

A finding from the cochrane neonatal Review Group shows that supplementation with probiotics significantly reduces the risk of sever necrotizing enterocolitis and mortality in preemies.

Enteral supplementation with probiotics (i.e., Lactobacillus, Bifidobacterium, and Saccharomyces species and Streptococcus thermophilus) significantly reduces the risk of severe (stage 2 or more) necrotizing enterocolitis (NEC) and mortality in premature infants weighing more than 1,000 g at birth.

The finding, representing a change in practice, comes from the Cochrane Neonatal Review Group and their analysis of nine relevant published randomized or quasi-randomized controlled trials including 1,425 infants.

The researchers calculated that enteral probiotic supplementation reduced the incidence of severe NEC by almost 70% (RR 0.32; 95% CI, 0.17–0.60) and the incidence of mortality by more than half (RR 0.43; 95% CI, 0.25–0.75). No important adverse effects were reported. They could not, however, find evidence of a significantly reduced risk for nosocomial sepsis or days on total parenteral nutrition.

Alfaleh K, Bassler D. Probiotics for prevention of necrotizing enterocolitis in preterm infants. Cochrane Database Syst Rev. 2008;(1):CD006181.

Cochrane Update: Probiotics for prevention of necrotizing enterocolitis in preterm infants. Obstet Gynecol. 2008;111:1202-1204.

Recent Videos
The significance of the Supreme Court upholding mifepristone access | Image Credit: unchealth.org
One year out: Fezolinetant displays patient satisfaction for managing hot flashes | Image Credit: sutterhealth.org
Addressing maternal health inequities: Insights from CDC's Wanda Barfield | Image Credit: cdc.gov
Addressing racial and ethnic disparities in brachial plexus birth Injury | Image Credit: shrinerschildrens.org
Innovations in prenatal care: Insights from ACOG 2024 | Image Credit:  uofmhealth.org.
Unlocking therapeutic strategies for menopausal cognitive decline | Image Credit: uclahealth.org.
Navigating menopause care: Expert insights from ACOG 2024 | Image Credit: mayo.edu.
raanan meyer, md
© 2024 MJH Life Sciences

All rights reserved.