A user-friendly nomogram can help answer the questions of newly diagnosed breast cancer patients about their patient-specific likelihood of developing sentinel lymph node metastasis, according to a report published in the Aug. 20 issue of the Journal of Clinical Oncology.
A user-friendly nomogram can help answer the questions of newly diagnosed breast cancer patients about their patient-specific likelihood of developing sentinel lymph node metastasis, according to a report published in the Aug. 20 issue of the Journal of Clinical Oncology.
Kimberly J. Van Zee, MD, of Memorial Sloan-Kettering Cancer Center (MSKCC) in New York City, and colleagues analyzed data from 3,786 sentinel lymph node biopsies to develop a model to predict the presence of breast cancer metastasis. From this they created a user-friendly prediction model, or nomogram.
The factors associated with sentinel lymph node metastasis were: age; tumor type, size, and location; lymphovascular invasion; multifocality; and estrogen and progesterone receptors. The nomogram was able to accurately discriminate the risk factors in individual cases and calculate the probability of metastasis to the lymph nodes.
Bevilacqua JL, Kattan MW, Fey JV, et al. Doctor, what are my chances of having a positive sentinel node? A validated nomogram for risk estimation. J Clin Oncol. 2007;25:3670-3679.
Hormone therapy safety: Study finds potential benefits for senior women
April 24th 2024A recent large-scale study challenged age-related concerns, suggesting hormone therapy may offer safety and even benefits for menopausal women aged over 65 years, aligning with The Menopause Society's 2022 Position Statement.
Read More
Hyperoxygenation use not linked to neonatal outcomes
April 23rd 2024Recent research evaluated the impact of maternal hyperoxygenation on neonatal Apgar scores, revealing no significant enhancement in outcomes among women with pathologic fetal heart rate tracing and suggesting limited efficacy of hyperoxygenation therapy in this context.
Read More
Study finds antihypertensive treatment reduces uterine fibroids risk
April 23rd 2024A recent study revealed that patients with untreated or new-onset hypertension face elevated chances of uterine fibroid diagnosis, underscoring the potential of antihypertensive therapy in mitigating this risk among midlife individuals.
Read More