
News|Videos|July 10, 2026
Highlighting zuranolone's real-world effectiveness on postpartum depression with Joy Baker, MD
Fact checked by: Joshua Fitch, Senior Editor , Nicole Canfora Lupo
The phase 4 study's oversampling of moderate PPD patients, showing a nearly 9-point EPDS drop by day 15, helps close a gap left by trials that enrolled predominantly severe cases.
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A phase 4, prospective, real-world study of zuranolone (Zurzuvae; Sage Therapeutics and Biogen) for postpartum depression (PPD) produced clinically meaningful symptom improvement across all baseline severities, findings that coauthor Joy Baker, MD, FACOG, PMH-C, C-EFM, MT(ASCP), said should increase clinician comfort in prescribing the oral treatment beyond severe disease.1,2
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