Obstetrics

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Using SSRI late in pregnancy may increase the risk of persistent pulmonary hypertension in a newborn. Plus, hormone therapy may help mood in early postmenopause; use of mesh for prolapse on the rise

The USPSTF updated recommendations on mammography have sparked discussion on screening in younger women. Plus, does exposure to gestational diabetes increase risk of autism? What are the implications of genome editing?

NASPAG 29th conference featured research on the increased risk of complications in teen pregnancy, the desire on over-the-counter contraception, and a tool to help identify patients with menorrhagia.

A recent report sheds light on how much false-positives and overdiagnosis of breast cancer cost. Additionally, new research examines the impact of the number of live births on future heart health in the mother and provides further evidence of the efficacy of cfDNA testing.

A form of assisted reproductive technology that could make it possible for women with mutations in mitochondrial DNA to give birth to children free of mitochondrial disease has been approved by UK’s House of Commons. A Food and Drug Administration (FDA) committee is considering granting similar approval for use of the technique-known as oocyte modification or three-parent gene therapy-in the United States.

Tight control of hypertension in pregnancy does not produce better perinatal outcomes or fewer serious maternal complications than looser control, according to results of an international randomized clinical trial. Published in the New England Journal of Medicine, the findings are consistent with those from a meta-analysis of 29 previous trials.

Results of a retrospective cohort study show that use of intracytoplasmic sperm injection is on the rise but cast doubt on whether the technology is improving reproductive outcomes. Brian Levine, MD, MS provides commentary.