SPOTLIGHT -
Oral sulopenem demonstrates non-inferiority to amoxicillin/clavulanate in phase 3 uUTI trial
Oral sulopenem (ORLYNVAH; Iterum Therapeutics) was non-inferior to amoxicillin/clavulanate for treating uUTIs in women, per the phase 3 REASSURE trial.
Government assistance boosts drug treatment access for women with OUD
New research shows women receiving Medicaid and support services are significantly more likely to receive treatment for opioid and drug use disorders.
High rates of uncertainty about having children reported
A new study reveals that nearly half of women who want kids are uncertain they'll follow through, shedding light on the complex emotions behind declining birth rates.
Molecular profiling reduces need for radiotherapy in endometrial cancer
A major clinical trial shows personalized treatment based on molecular profiling can safely cut radiation use in nearly half of women with high-intermediate risk endometrial cancer.
New test identifies hereditary cancer presence with high accuracy
Researchers developed a CRISPR-Select assay to classify BRCA gene variants, improving early breast and ovarian cancer detection.
Prenatal mycotoxin exposure linked to lower birthweight
A new study finds that exposure to mycoestrogens during pregnancy may reduce birthweight and impair placental efficiency, with climate change expected to increase exposure risks.
Neal Barnard, MD, FACC, highlights AMA's new breast cancer prevention guidelines
The American Medical Association urges plant-based diets, exercise, and reduced alcohol to lower breast cancer risk and address racial disparities.
Exposure to wildfire smoke and heat linked to worse birth outcomes in climate-vulnerable areas
Wildfire smoke and heat stress before and early in pregnancy raise the risk of SGA births, especially in climate-vulnerable neighborhoods.
Third-trimester hyperglycemia in pregnancy linked to adult obesity in offspring
Higher third-trimester glucose levels in insulin-dependent pregnancies are tied to increased obesity risk in adult offspring, a 40-year study finds.
Contemporary OB/GYN week in review: ACOG statement, contraception guidance, and more
Review some of the top stories from the Contemporary OB/GYN website over the last week, and catch up on anything you may have missed.
Zachary Wagner, PhD, discusses the harms of bias in reproductive care
A new study reveals how provider bias and stigma in reproductive health settings limit care for young, unmarried, and childless women—and how targeted interventions can help reduce these barriers.
Ciera Kirkpatrick, PhD, shows how TikTok is transforming cervical cancer awareness
Health care providers are using short-form videos on TikTok to educate young women about Pap tests, breaking down barriers with engaging, accessible content.
Maria Gallo, PhD, discusses high attendance at crisis pregnancy centers
New research shows up to 17% of reproductive-aged women visit crisis pregnancy centers, raising alarms over misinformation and lack of regulation.
Prenatal exposure to PFAS linked to higher adolescent blood pressure in diverse birth cohort
In a recent study, prenatal PFAS exposure was linked to higher adolescent blood pressure, with stronger effects in boys and children born to non-Hispanic Black mothers.
ACOG condemns violence against reproductive health care providers
In response to recent threats and attacks, the American College of Obstetricians and Gynecologists urges stronger protections for clinicians and reaffirms support for safe, accessible reproductive care.
Mail-in HPV self-tests found to double cervical cancer screening rates
A new study finds that mailing human papillomavirus self-collection kits, especially with patient navigation support, significantly boosts cervical cancer screening rates.
Prenatal hypertension exposure linked to higher seizure risk in children
A new study reveals that children born to mothers with high blood pressure during pregnancy face a significantly increased risk of seizures, potentially because of brain inflammation.
AAP issues updated guidance on contraception for adolescents
The American Academy of Pediatrics urges clinicians to offer confidential, adolescent-centered contraceptive care using evidence-based, equity-informed approaches.
Night shift work linked to higher asthma risk in women
A large study finds that women working night or irregular shifts face significantly higher odds of moderate to severe asthma, unlike their male counterparts.
Endometriosis linked to higher risk of autoimmune diseases
New research reveals that women with endometriosis face increased risks of rheumatoid arthritis, osteoarthritis, and multiple sclerosis because of shared genetic and immune pathways.
High rates of pain and heavy bleeding found in teens with endometriosis
A study of adolescents with pathology-confirmed endometriosis reveals common symptoms such as progressive dysmenorrhea and heavy bleeding.
Contemporary OB/GYN week in review: Preeclampsia screening, BV treatment, and more
Colorectal cancer tied to long-term sexual health risks in women
A recent study found that women with colorectal cancer face an increased long-term risk of pain during sex, early menopause, and pelvic disease.
Insulin resistance linked to abnormal uterine bleeding
A new study suggests a strong association between hyperinsulinemia and abnormal uterine bleeding, pointing to shared risk factors that could inform future prevention and treatment strategies.
Similar IVF outcomes reported for PPOS and GnRH antagonist protocols
A retrospective study finds comparable pregnancy rates between PPOS and GnRH antagonist protocols, with a trend toward improved blastocyst outcomes in PPOS cycles.
Postmortem ultrasound accurately estimates gestational age
A new study shows extrauterine cerebellar ultrasound is a reliable, low-cost method to assess gestational age after fetal or neonatal death, especially in low-resource settings.
Early RSV vaccination in pregnancy boosts antibody transfer to newborns
Vaccinating pregnant women at least 5 weeks before delivery significantly improves transplacental transfer of respiratory syncytial virus antibodies, offering better early protection for infants.
Study finds childhood adversity linked to elevated risk of endometriosis
Childhood adversity may raise endometriosis risk, with exposure to violence linked to a twofold increase, a Swedish study finds.
Secnidazole shows promise for recurrent BV treatment in new clinical trial
A recent study presented at ACOG 2025 highlights the potential of once-weekly secnidazole oral granules as an effective long-term therapy for recurrent bacterial vaginosis.
MRI study links eclampsia to cerebral infarcts, edema, and vasospasm
New research reveals that women with eclampsia show significantly higher rates of brain abnormalities, offering insight into unexplained neurologic symptoms during pregnancy.
