Less may be more when it comes to preserving bone with estradiol
Endogenous estradiol levels above 10 pg/mL and higher levels of endogenous testosterone decrease the bone remodeling rate and protect bone mass in women 65 years of age or younger. The new estradiol data are much lower than the 40 to 60 pg/mL that has been cited in the older literature. In this population, estradiol levels higher than 10 pg/mL were associated with a higher bone mineral density (BMD) of the lumbar spine (+14%, P
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Trimethoprim–sulfamethoxazole not found to increase infant birth weight in HIV cases
July 9th 2025A recent randomized trial found no significant improvement in birth weight or key birth outcomes from antenatal trimethoprim–sulfamethoxazole prophylaxis in human immunodeficiency virus-positive pregnant women.
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