SMFM statement on NIH treatment guidelines


SMFM supports the new NIH COVID-19 Treatment guidelines.

SMFM supports the new NIH COVID-19 Treatment guidelines.

The following pertains to treatment for pregnant patients:

  • Paxlovid (nirmatrelvir [PF-07321332] tablets and ritonavir tablets): no pregnancy data on nirmetrelvir, limited supply, consider drug-drug interactions
  • Sotrovimab: limited supply that is mostly reserved for highest risk immunocompromised and elderly
  • Remdesivir (3 day outpatient regimen): extensive pregnancy experience but requires multiple infusions

All of the above have similar efficacy at preventing hospitalization and death; despite no pregnancy-specific data

  • Molnupiravir: 30% efficacy; EUA recommends against use in pregnancy but may reasonably consider use in pregnancy if no other therapies available and with documented counseling
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