Bob Kronemyer

Combined oral contraceptives were found to be moderately more efficacious than placebo for treating overall premenstrual symptomatology in women with premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD).

A study in the International Journal of Gynecology & Obstetrics found that transperineal ultrasound (TPU) signs of pelvic floor muscle hypertonia are more prevalent in endometriosis patients with chronic constipation than in those without.

Women with severe menopausal symptoms are likely to experience significantly greater cognitive decline than their counterparts with mild menopausal symptoms, according to a cross-sectional study in the journal Menopause.

For preeclampsia, multifetal gestation was the most common high-risk factor among pregnant patients who gave birth in the United States in 2019.

Research in the journal Cell Reports concludes that the discovery of a hormone-sensing pathway in Candida albicans, which enables the fungus to adapt to estrogen, could help explain gender biases linked to fungal infections and might provide an alternative approach to improving women's health.

Women with non-albicans Candida (NAC) vulvovaginal candidiasis (VVC) were nearly twice as likely to have multiple physician visits for recurring infections compared to women who had C. albicans (CA) VVC, according to a retrospective chart review in the Journal of Women’s Health.

An oral probiotic formula for the secondary prevention of vulvovaginal infections in pregnant women neither colonized in the vagina nor reduced the rate of repeated vulvovaginal infection, according to a study in the American Journal of Gynecology & Obstetrics.

A phase 2, multicenter study has found relugolix (Myfembree; Myovant Sciences) significantly decreases menstrual blood loss in women with uterine leiomyomas and is mostly well tolerated. Relugolix is a small molecule gonadotropin-releasing hormone (GnRH) receptor antagonist.

A clinical study has confirmed that the pathophysiology of recurrent vulvovaginal candidiasis (RVVC) relies primarily on Candida albicans (C. albicans)-specific attributes like hyphal morphogenesis, biofilm formation and pathogenesis that differentiate it from other prominent non-albicans C. (NAC) species.

Autophagy is a controlled lysosomal degradation pathway that protects cells and allows to overcome cell death.

The authors noted that both primary options for treatment are currently being debated as to their efficacy and safety.

A case report of infiltrative endometriosis without endometrioma underscores the need to consider endometriosis in the differential for patients with pelvic masses and to recognize possible features that might indicate the diagnosis.

Among women with vulvovaginal candidiasis (VVC) or recurrent VVC (RVVC), the 3 most common signs and symptoms are itching (91.2%), burning (68.3%), and redness (58.1%), according to an online patient survey in BMC Womens Health.

Because the mechanism of action of medical-grade honey (MGH) is based on enhancing wound healing and exerting strong broad-spectrum antimicrobial activity, MGH may also help to treat recurrent vulvovaginal candidiasis (RVVC), according to a review in the Journal of Fungi.

A literature search revealed there is no international agreement on how to characterize or classify endometriosis.

Because many groups have a stake in newborn screening, “Who will take responsibility for integrating varying perspectives to modernize newborn screening?” Bailey pondered. “Funding and auspice will be critical decisions.”

Pooled estimates for chlamydia and/or gonorrhea were also null, but LARC users were significantly more likely to contract trichomoniasis infection compared to oral contraceptive users.

Half of prisons and over 80% of jails in the United States allowed postpartum permanent contraception, according to a study in the journal Contraception.

The findings support previous research demonstrating that increased access to emergency contraception does not compromise use of other more effective methods or lead to an increase in reported levels of unprotected sexual intercourse, according to Hawkins.

Many adolescents across the United States lack quality sex education, a trend that has worsened in recent years. Moreover, national statistics mask significant inequities in the receipt of formal sex education by gender, race and ethnicity, sexual orientation, and the location of instruction, according to a study in the Journal of Adolescent Health.

“The results suggested that weight maintenance or weight loss should not be used as routine guidelines,” The authors concluded.

To the investigators’ surprise, routine perinatal visits had the greatest impact on PROM in pregnant women with VVC.

A cross-sectional analysis of the Boston Birth Cohort (BBC) from 1998 to 2016 has found that maternal nativity and duration of United States residence were linked to preeclampsia among non-Hispanic Black women, but not among Hispanic and non-Hispanic White women, after adjusting for sociodemographic and cardiovascular risk factors.

Being Non-Hispanic (N-H) Asian is a significant influencing factor for the number of gastrointestinal (GI) symptoms and the severity scores of GI symptoms, according to a study of 4 major racial/ethnic groups of midlife women in the United States.

Lactobacilli are the presiding members of the healthy human vaginal microbiota and are considered the first defense line from pathogen infection, including vulvovaginal candidiasis (VVC), whereas biofilm is the predominant microbial growth form in nature.

A home kit to detect urinary tract infections (UTIs) like Candida albicans from vaginal fluids on sanitary napkins and tampons could soon enter the clinical phase.

According to a recent study, women who experience stable menstrual cycles during the menopause transition have a significantly higher cardiovascular disease (CVD) risk later in life than those who have a late increase in cycle length.

A prospective observational screening study has concluded a cytology dual-stain (DS) biomarker effectively triages women who test positive for primary human papillomavirus (HPV) and are at higher risk of developing cervical cancer, irrespective of the HPV genotype.

Human papillomavirus (HPV) vaccination has significantly decreased the incidence and mortality of cervical cancer in girls and women between the ages of 15 and 24, according to a research letter in JAMA Pediatrics.

Many of the glaring disparities that exist in care for the 26 million women in the United States who suffer from uterine fibroids, which disproportionately affects up to 80% of Black women, are being aggressively addressed though a new multifaceted campaign called UNmuting Fibroids.