Endometriosis

Researchers from a study published in Cancers discovered a new method of detecting endometrial cancer in women via a simple, non-invasive blood test.

Research indicates that women with endometriosis are prone to physical, psychosocial, social, and sexual disturbances and obstetrical complications, according to a literature search of the impact of endometriosis on various aspects of reproductive health in the Journal of Obstetrics and Gynaecology.

A prospective study in the journal Ultrasound in Obstetrics & Gynecology has found that women treated with pelvic floor physiotherapy showed a significant improvement in pelvic floor relaxation, superficial dyspareunia and chronic pelvic pain, in comparison to women who did not receive treatment.

A study in the Journal of Obstetrics and Gynaecology found that dienogest was effective in decreasing the size of endometrioma and reducing endometriosis-associated pain, along with a favorable safety and tolerability profile.

A study of 30 women who had their post-cesarean section abdominal wall endometriomas (AWE) surgically removed found that the main symptom for detection and for surgery in two-thirds of cases was cyclic pain, whereas 13.3% of patients had no symptoms.

“We need to find a good balance between conservative and surgical treatment,” said principal investigator Sylvia Mechsner, MD.

For treating inflammatory pain in endometriosis, inflammatory factors that promote angiogenesis and neuroangiogenesis are encouraging targets, according to a systematic review in the journal Biomedicines.

In the largest meta-analysis study to date, researchers find that a levonorgestrel-intrauterine system (LNG-IUS) used for 3 to 6 months is likely more effective than non‐intrauterine progestogens for reversing endometrial hyperplasia (EH).

Seven women’s health-focused organizations have formed the Alliance for Endometriosis to improve the lives of women afflicted with the disease.

Inflammation, neurogenic inflammation, neuroangiogenesis, peripheral sensitization and central sensitization all contribute to chronic pain in endometriosis, according to a review in the journal Frontiers in Cellular Neuroscience.

The risk of opioid use after endometriosis diagnosis is significantly greater in patients who used opioids before diagnosis, according to a retrospective analysis of data from a large health database.

Laparoscopic management of deep endometriosis involving the sacral roots and the sciatic nerve improves patient symptoms and overall quality of life, according to a retrospective case series.

With patient-centered care being the mantra of 21st-century medicine, the decision to proceed with fertility surgery in women with endometriosis should be based on the individual patient, her reproductive expectations, her specific disease pattern, her support, family network, and available health care resources.

“As surgeons, our primary goal is to make patients feel better and we often accomplish this by surgically treating endometriosis,” said co-author Ally Murji, MD, MPH, an associate professor of ob/gyn at the University of Toronto and Mount Sinai Hospital in Toronto, Canada.

A new study by French investigators shows that adenomyosis confined to the outer myometrium is associated with primary infertility—but not more diffuse disease.

Self-catheterization for over 1 month occurred in 13.6% of surgical cases, mainly after segmental colorectal resection.

Presented by Kristen Pepin, MD, and Jon I. Einarsson, MD, PhD, MPH Brigham and Women’s Hospital, Boston

A genome-wide analysis sheds light on how hormone response in endometrial cells affects endometrial function.

Researchers sought to investigate the effects of endometrioma and the impact of bilaterality on in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) outcomes.

The American Academy of Pediatrics has released new information to improve long-acting reversible contraception (LARC) access for teenagers.

Nearly two-thirds of women newly diagnosed with endometriosis filled an opioid prescription within the first year, according to a US population-based claims study.

The first study to characterize endometriosis in transmasculine individuals has concluded that evaluation for endometriosis with dysmenorrhea is limited in this unique population

A prospective observational study has assessed the clinical relevance of endometrial thickness and abnormal uterine bleeding to endometrial cancer risk in a cohort of postmenopausal patients undergoing diagnostic hysteroscopy and endometrial biopsy.

The North American Society for Pediatric and Adolescent Gynecology offers a patient handout on endometriosis. Continue reading for more.

An external validation multicenter international study, in the hands of expert ultrasound examiners, has concluded that the ultrasound-based endometriosis scoring system (UBESS) is accurate in predicting the level of surgical complexity in the presence of bowel deep endometriosis or obliterated pouch of Douglas.