Endometriosis

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A genomic analysis of endometriotic lesions shows that a disease associated with almost no risk of malignant transformation may harbor mutations associated with cancer. The findings, published in NEJM, provide a rationale for characterizing all endometriosis subtypes, say the authors.

New research on two different dosages of elagolix show that both doses improved dysmenorrhea and nonmenstrual pelvic pain in women with endometriosis. The findings, published in NEJM, add to data from previous studies of the drug, which showed that it produced partial to nearly full estrogen suppression.