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While obesity has been shown to have a strong correlation with an increased risk of breast cancer in postmenopausal women, the results from a large-scale, multicenter analysis show that the inverse may actually be true for younger women. PLUS: Women with denser breast tissue have higher recall and biopsy rates and increased odds of screen-detected and interval breast cancer, according to a recent study.

An analysis by Danish investigators published in JAMA shows that taking oral fluconazole during pregnancy is associated with a significant increased risk of spontaneous abortion. Plus: What persuades parents to vaccinate for HPV? Also: Does prenatal exposure to lithium increase risk of congenital malformations?

Ob/gyns have a responsibility and can no longer be passive in this genomic era.

Readers respond to an editorial from Dr. Lockwood on hormonal contraception and breast cancer as well as an editorial on burnout and depression in medical students.

The goal of this article is to review these challenges and the evidence behind measures to address challenging IUD insertions.

Two Contemporary OB/GYN readers share their experiences with losing a patient.

Gynecologists are faced with a number of hereditary cancer tests. Understanding benefits and limits is key to counseling patients.

Mother-to-child transmission of HIV in the United States can be eliminated with the help of obstetricians.

Ob/gyns can take simple steps to help patients understand their personal health information, promoting better outcomes.

A recent study compared pretreatment with mifepristone followed by treatment with misoprostol against treating with misoprostol alone for the management of  first-trimester pregnancy loss. Plus: Are patients less satisfied with MDs who reduce opioids? Also: Does infant exposure to hypertensive disorders or pregnancy affect neurodevelopment?

Expert commentary on Practice Bulletin No. 186: Long-Acting Reversible Contraception: Implants and Intrauterine Devices.

Recognition and management of sepsis and septic shock in pregnant women remain a challenge, despite several advances made in the non-pregnant patient population. This article will review how to recognize sepsis and key principles for management of the condition in pregnant patients.

Although gabapentin is recommended and commonly prescribed for vulvodynia, its value in such cases is usually associated with complaints that have neuropathic components, such as dynamic allodynia.

The experimental agent TX-004HR effectively improved the vaginal mucosa of postmenopausal women with vulvovaginal atrophy (VVA) and reduced moderate-to-severe dyspareunia and vaginal dryness compared to placebo, according to results of a trial.

Results of a study by Canadian researchers suggest that exposure to low and medium doses of cranberry juice may have potential to reduce physician visits and costs for women who have a history of recurrent urinary tract infection (UTI).

Results of a Phase 3 randomized clinical trial (RCT) suggest that a combination carbapenem/beta-lactamase inhibitor may have potential in treatment of severe drug-resistant gram-negative urinary tract infections (UTI).

Have you broached the topic of frozen embryos with your patients? What was their response?

According to research recently published in The New England Journal of Medicine, chemotherapy is not more beneficial than treatment with hormone therapy alone for women with certain types of breast cancer. Plus: Do abortions cause depression? Also: Public comments are being solicited on a new systematic review from the US Preventive Services Task Force (USPSTF) on unhealthy alcohol use in adults aged 18 and older, including pregnant women.

A new self-administered scale to assess painful symptoms of endometriosis in research trials was recently developed by European obstetrician/gynecologists, the first time such a scale has been created with input from both clinicians and patients.

Meta-analysis of 3 studies of acupuncture for relief of endometriosis-related pain found positive results for reduction in pain intensity, according to recently published research.

The first birth from a groundbreaking trial of in utero stem cell transplantation suggests that fetal therapy may be a viable new option for alpha thalassemia (ATM). Plus: Why do vasomotor symptoms bother some women long after menopause? Also: Does CPAP improve sexual QOL in women with sleep apnea?

Results of a UK study show that while intrauterine infection may contribute to preterm birth (PTB), a reproducible “preterm placental microbiome” does not exist. Plus: Depression in the male partner of couples being treated for infertility was linked to lower pregnancy chances, according to results of a recent study.

Prenatal exposure to tobacco and marijuana can affect infant size and behavior, according to a recently published study. Plus: Is HT-NIPT cost-effective for guiding postpartum use of anti-D? Also: A recent study shows that lesbian and bisexual (LB) women have a greater likelihood of developing type 2 diabetes (T2D) than their heterosexual counterparts.

Understanding the psychological underpinnings of sexual motivation can be helpful in improving the sexual and relationship well-being of couples affected by vulvodynia, according to recent research.

A small study shows that treatment with CO2 laser induces histological changes in the epithelium and lamina propria that may result in improvement in symptoms associated with vulvovaginal atrophy (VVA).

A recent study shows that mothers exposed to moderate to high levels of caffeine during pregnancy may give birth to infants that gain excess weight in early childhood. Plus: How does ART affect risk of stillbirth? Also: A study found that obese African-American women have significantly lower energy expenditure per kilogram of mass compared to obese white women with similar energy intake and physical activity levels.

Maternal chronic hepatitis B virus (HBV) infection is associated with a 16% increase in risk of preterm birth (PTB), with substantial heterogeneity, according to an updated systematic review and meta-analysis.

The fetal fibronectin (fFN) test alone had a sensitivity of 66.7% and a specificity of 97.2% in predicting spontaneous preterm birth (SPTB) in symptomatic twin pregnancies, according to a small pilot study of 40 women.