
Prophylactic salpingo-oophorectomy has been widely recommended for women with BRCA1 or BRCA2 mutations based on evidence from retrospective studies that have found a strong protective effect against cancers of the ovary and fallopian tube. Now a new international prospective study that included approximately 1,800 women with germline BRCA1 or 2 mutations has found the procedure reduces the overall risk of ovarian, tubal and peritoneal cancers by 80%.
