Uterine evacuation in the office
July 1st 2005Outpatients undergoing early uterine evacuations in your office require a safe environment and a clinician with a thorough knowledge of the medical and surgical techniques. This practical review provides protocols for medical abortion and early pregnancy failures and guides you through the manual vacuum aspiration procedure.
Grand Rounds: Counseling couples on risks of early preterm delivery of triplets
July 1st 2005Cervical length assessment is just one of several powerful tools for detecting or excluding patients at risk for preterm birth. An expert tells how to assess and counsel a patient pregnant with triplets on her chances of carrying all three fetuses to at least 32 weeks.
Preventing pregnancy loss with aspirin and low-molecular-weight heparin
July 1st 2005Low-dose aspirin combined with low-molecular-weight heparin (LMWH) during pregnancy is just as safe and effective as aspirin with unfractionated heparin (UFH) for preventing recurrent pregnancy loss due to antiphospholipid syndrome, according to a prospective, controlled, multicenter pilot study.
Editorial: Caduceus—or Asklepian?
July 1st 2005The caduceus is the modern American symbol of the medical profession. But the Asklepian, which I encountered on a recent trip to the Greek island of Kos, may be a far better emblem for the values we as ob/gyns hold dear. Allow me to explain the import of two snakes versus one.
Grand Rounds: Prolonged pregnancy: How long do you wait?
June 1st 2005Postterm birth seems to get a lot less attention than preterm birth when clinicians are discussing the risks of complications and death. But, unlike babies born too soon, timely delivery can almost entirely prevent the risks—including stillbirth—linked with prolonged pregnancy.
Editorial: Who will follow in our footsteps?
June 1st 2005As I write this I am post-call, which may account for the tone of my meandering discourse. At my age, the problem is not so much taking call but surviving the next day. While tackling clinical challenges can be exciting, what I find most stimulating is the chance to teach and learn from my residents.
Redefining the Family Cancer History
May 12th 2005There's a good chance that you are asking the wrong questions and not enough questions when it comes to taking family cancer histories. "It is not enough to ask 'Did anybody in your family die of cancer, yes or no?'" said Louise Strong, MD, Section Head of Clinical Cancer Genetics and Professor of Cancer Genetics at the University of Texas M.D. Anderson Cancer Center in Houston, TX.
1-Year Results Favor Monthly Ibandronate Dosing Over Daily
May 12th 2005First-year data from the 2-year MOBILE study of monthly administration of ibandronate for postmenopausal osteoporosis have been released. All women achieved significant response, but women taking the agent once a month had a greater increase in bone mineral density (BMD) than similar women taking the drug on a daily schedule.
Women Prefer Monthly Dosing for Osteoporosis
May 12th 2005Women being treated for osteoporosis expressed an overwhelming preference for monthly dosing over weekly dosing in a recent nationwide survey. The study, directed by Wulf Utian of The Cleveland Clinic in Cleveland, OH, supports the monthly dosing schedule offered by ibandronate, a competing oral bisphosphonate.
BMD Recovers After Discontinuing DMPA Contraception
May 11th 2005Intramuscular injection of depot medroxyprogesterone acetate (DMPA) is a highly effective and popular form of contraception. It is used by about 2 million women in the US and 25 million women worldwide, according to Andrew Kaunitz, MD, from the University of Florida Health Science Center in Jacksonville, FL.
Concomitant Tubal Sterilization and Endometrial Ablation Safe
May 11th 2005Is concomitant sterilization using the ESSURE method with Thermachoice III endometrial ablation feasible and safe? Absolutely yes, said Rafael Valle, MD, from Northwestern University Medical School in Chicago. Data presented during the second session of Papers on Current Clinical and Basic Investigation yesterday afternoon helped convince the Food and Drug Administration to approve the combination procedure.
Uterine Fibroid Embolization Most Cost-Effective Treatment
May 11th 2005Cost effectiveness may change the way physicians treat uterine fibroids. The newest procedure, uterine fibroid embolization (UFE) offers financial advantages over hysterectomy or myomectomy for insurers, hospitals, and the health-care system.
Cryoablation Benefits Continue Into Second Year
May 11th 2005Cryoablation has been reported as an effective treatment for abnormal uterine bleeding in the short term, but longer-term data have been lacking. New data from Raffaele Bruno, MD, and a research team at Lahey Clinic in Burlington, MA, indicate that cryoabalation is also effective into the second year after treatment.
Hormone Choice Can Affect Bleeding Patterns in Continuous OC
May 11th 2005A growing number of physicians and patients are looking to continuous use of oral contraceptives (OCs) to reduce the number of menstrual days and provide other quality-of-life improvements. But there are unanswered questions about the effect of different hormones used in OC on bleeding patterns.
Lasofoxifene Improves Vaginal Atrophy in Phase III Trial
May 11th 2005Phase II studies have shown that lasofoxifene, a next-generation selective estrogen-receptor modulator, increased bone mineral density and improved both objective measures of vaginal atrophy and reported symptoms. Margery Gass, MD, and a team from the University of Cincinnati Medical Center reported yesterday that a double-blind, randomized, placebo-controlled Phase III trial produced similar results.