Depot and Daily GnRHa: Equally Effective for Long Down-Regulation Protocol?
For the long protocol of down regulation in in vitro fertilization (IVF) cycles, are depot and daily gonadotropin-releasing hormone agonists (GnRHa) equally effective?
Evidence Doesn’t Support a 1-step Approach to Diagnosing Gestational Diabetes
An independent panel convened by the National Institutes of Health has concluded that there is insufficient evidence to adopt a 1-step approach to the diagnosis of gestational diabetes mellitus (GDM).
Robotic Hysterectomy Offers No Benefits Over Laparascopic Hysterectomy
The use of robotically assisted hysterectomy for women with benign gynecological disease offers little short-term benefit and has significantly greater costs than laparoscopic hysterectomy, according to the results of a large US cohort study.
Is Fertility Improved After Hysteroscopy for Uterine Cavity Abnormalities?
Hysteroscopic removal of polyps in women with unexplained infertility may increase their chances of becoming pregnant, concludes an intervention review conducted by the Cochrane Menstrual Disorders and Subfertility Group.
Metformin Is an Effective Alternative to Insulin in Gestational Diabetes Mellitus
In patients with gestational diabetes mellitus, metformin is an effective alternative to insulin, according to the findings of a recent single-center randomized controlled study.
Bevacizumab Improves Survival but Reduces Quality of Life in Late-Stage Cancer Patients
Patients with stage IVB, recurrent, or persistent cervical cancer that was not cured with standard treatment who were given the angiogenesis inhibitor bevacizumab lived 3.7 months longer than patients who did not receive the drug, but adverse events increased.
The Unintended Consequences of Giving Acetaminophen to Newborns
A study assessing the effectiveness of acetaminophen for neonatal pain relief found that use of acetaminophen shortly after birth may aggravate a subsequent stress response.
Adhesive Surgical Drapes May Cause, Not Prevent, Infection
There is no evidence that plastic adhesive surgical drapes reduce surgical site infection rates, and some evidence that these drapes may increase infection rates, according to a third update of an intervention review and analysis conducted by the Cochrane Wounds Group.
Low Levels of Vitamin D, Trace Elements Linked to Premature Ovarian Failure
Vitamin D deficiencies are common in women with primary ovarian insufficiency (POI), and serum levels of zinc, copper, and vitamin D appear to correlate with hormonal status, concluded a recent cross-sectional, case-control study.
Anti-D: Does Method of Administration Make a Difference?
Intramuscular anti-D and intravenous anti-D administered in the 28th week of pregnancy are equally effective for the prevention of Rhesus alloimmunization during pregnancy, according to a new intervention review conducted by the Cochrane Pregnancy and Childbirth Group.
Desvenlafaxine Effectively Reduces Moderate to Severe Hot Flashes
In clinical trials, 12 weeks of desvenlafaxine effectively treated moderate to severe hot flashes in postmenopausal women, and the benefit remained after 1 year of maintenance treatment.
Technique Rules Out DVTs in Pregnant Women, Eliminates Unnecessary Anticoagulation Meds
Serial compression ultrasonographic testing in conjunction with Doppler imaging can reliably rule out blood clots in the legs of women who are pregnant, according to new study findings.
Efficacy of Quick Start Hormonal Contraception
Immediate start of hormonal contraception may reduce unintended pregnancies and increase method continuation, but the evidence is limited, according to the findings of an intervention review conducted by the Cochrane Fertility Regulation Group.
Better Classification Systems Needed for Genitourinary Fistulas
The current genitourinary fistula classification systems have poor to fair prognostic value, as does an empirically derived scoring system that predicts fistula closure 3 months after surgery, according to the findings of a new prospective cohort study.
Internal Versus External Tocodynamometry: Which Has Better Outcomes?
Monitoring uterine contractions with internal tocodynamometry (IT) versus external tocodynamometry (ET) results in similar maternal and neonatal outcomes in women whose labor is induced or augmented with oxytocin.
mRNA-Based HPV Assay Performs Well for Triaging Colposcopy Referrals
The use of APTIMA human papillomavirus (AHPV) assay for the detection of high-risk human papillomavirus E6/E7 oncogenic messenger RNA is an effective triage method for colposcopy referral in women with atypical squamous cells of undetermined significance cytology (ASC-US).
Migraine With Aura Contributes to Cardiovascular Events and Blood Clots
Women who have migraine with aura, especially those who take combined hormonal contraceptives (CHCs) have an increased risk for cardiovascular or thrombotic events.
Botox for Overactive Bladder Approved by FDA
On January 18, 2013, the FDA announced its approval of onabotulinumtoxinA (Botox) for the treatment of overactive bladder in adults who cannot use or who do not respond adequately to anticholinergic medications.
Vaginal Delivery Is Best for Patients With Pelvic Girdle Pain
Patients with pelvic girdle pain during pregnancy who had a cesarean section were more likely to experience persistent pain 6 months after delivery than patients who delivered vaginally, according to a new follow-up study from the Norwegian Institute of Public Health.
The Most Hotly Anticipated Ob/Gyn Research of 2013
New drugs, new research, new guidelines… there’s a lot for ob/gyns to look forward to in the coming year. Here, the leaders of seven ob/gyn societies share the most interesting, important, exciting things on their radar for 2013.
The Leadership Report: The Best Ob/Gyn Research From 2012
From ASRM’s removal of the ‘experimental’ label from the procedure of oocyte cryopreservation, to discoveries into the complex genetic processes involved in ovarian cancer, 2012 was another important year in ob/gyn research. Here, the leaders of seven major ob/gyn societies reflect on the most exciting research of the last year.
Change the Name of “PCOS,” Panel Recommends
An independent panel convened by the NIH has concluded that the name “polycystic ovary syndrome (PCOS)” causes confusion and is a barrier to progress in the realms of both research and effective patient care.
Nonnarcotic NSAID Is Safe for Postoperative Pain Control
Continuous infusion of the NSAID ketorolac, a powerful nonopioid analgesic, is a safe therapeutic option for the management of postoperative pain, concludes a double-blind randomized controlled trial.
Current Evidence Favors Blunt Hysterotomy for Cesarean Deliveries
In lower-segment cesarean deliveries, blunt dissection of the uterine incision is associated with less blood loss than sharp dissection, according to the findings of a recent systematic review and meta-analysis.
Best Treatments for Overactive Bladder Syndrome
The symptoms of overactive bladder syndrome were most improved when patients used anticholinergic drugs either alone or in combination with bladder training exercises, according to the results of an intervention review and meta-analysis conducted by the Cochrane Incontinence Group.
Effective Ways to Prevent Preterm Birth in High-Risk Women
Both vaginal progesterone and cervical cerclage can effectively prevent preterm birth in women at risk for spontaneous preterm birth, according to the results of an adjusted indirect meta-analysis of randomized controlled trials.
Managing Postmenopausal Symptoms With Nonpharmacological Therapies
Certain herbal and complementary medicines may be a valuable treatment option for women with postmenopausal symptoms, according to a new review outlining the advantages and limitations of the available treatments of postmenopausal symptoms.
Delay Pregnancy at Least 12 Months After Bariatric Surgery, Review Suggests
Women should wait 12 to 18 months after weight-loss surgery before trying to become pregnant, according to an evidence-based literature review.
Do Psychosocial Interventions Improve Quality of Life After a Cancer Diagnosis?
Nurse-delivered interventions that combined psychoeducation with supportive attention may help improve mood in patients in whom cancer has been newly diagnosed.
Skin Closure Technique Impacts Risk of Cesarean Wound Disruption or Infection
After a cesarean delivery, closing the incision with staples, compared with sutures, is associated with significantly more composite wound morbidity, according to the results of a new randomized controlled trial.
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