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The authors noted that, although recent guidelines embrace using history of menopause before age 40 to refine atherosclerotic cardiovascular disease (ASCVD) risk assessments in middle-aged women, “robust data on cardio-vascular disease risk in this population is lacking.”

Metastatic Breast Cancer

Australian researchers believe that PD-L1 may have potential as an indicator of potential response to chemotherapy in women with metastatic breast cancer. That was based on results of a randomized trial, presented at the European Society for Medical Oncology in Lugano, Switzerland.

Accelerated biological aging was seen in women who had severe menopausal vasomotor symptoms (VMS) on enrollment in the Women’s Health Initiative Observational Study (WHI-OS), or late-occurring VMS (at enrollment but not at/during their reported menopause transition, according to a study in The Journal of Clinical Endocrinology & Metabolism.