Pregnancy and Birth

A retrospective study of more than 3200 cesarean deliveries found that patients with three or more prior cesareans have a 15% likelihood of a uterine window, supporting consideration of early-term delivery in this group.

Lam-Rachlin reported that the software did not add time to the examinations and, in some instances, appeared to speed up the process by providing a rapid preliminary analysis.

A randomized clinical trial found that weekly extended-release buprenorphine achieved significantly higher illicit opioid abstinence during pregnancy compared to daily sublingual doses.

A national EHR database study found that GLP-1 RA prescribing among perinatal patients increased more than thirtyfold between 2019 and 2024, with an estimated 20,000 pregnant individuals exposed in 2024 alone.

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A large preconception cohort study found that nearly 41% of pregnancy planners tested more than 4 days before their expected period, a pattern associated with a fivefold higher risk of false-negative results and threefold higher detection of very early pregnancy losses.

Adnan I. Qureshi, MD, reports that women with a history of stroke have 2-fold higher odds of recurrence during pregnancy and the 6-week postpartum period.

Sara Perelmuter advocates for routine postpartum screening and provider education on lactation-safe therapies when dealing with GSL symptoms.

A longitudinal study found that third-trimester levels of sFlt-1 and hs-cTnI were an independently associated with higher long-term CVD risk.

A large insurance database study found that more than 80% of pregnant patients with depression or anxiety discontinued SSRI/SNRI therapy, which was associated with nearly double the rate of mental health emergencies compared to those who continued treatment.

Sara Perelmuter details how naming Genitourinary Syndrome of Lactation (GSL) is a vital step in addressing the treatment gap in postpartum care.

Standardized, patient-completed screening for substance use at delivery admissions reduced racial disparities in urine toxicology testing while improving testing efficiency, according a study from Mariam Naqvi, MD, and colleagues.

An expert infectious disease panel discusses how recent federal vaccine schedule changes can impact maternal immunizations and potential repercussions.

Research indicates that LMWH prophylaxis effectively mitigates the high risk of pregnancy loss and reduced natural fecundity associated with protein S deficiency.

An expert infectious disease panel discusses how recent federal vaccine schedule changes can impact maternal immunizations and potential repercussions.

In a 29-state review of 2017–2019 data, 86.4% of pregnancy-related infection deaths were deemed preventable, with genital tract infections, group A streptococcus, and delays in antibiotics emerging as key targets for intervention.

The FDA has cleared a cloud-based AI tool that predicts delivery dates solely from ultrasound images.

A Finnish registry study indicates that women with endometriosis have a 51% higher risk of miscarriage and a 2-fold increased risk of ectopic pregnancy compared to controls.

A global analysis found significant disparities in magnesium sulfate use for preterm birth, particularly between higher- and middle-income countries.

Very early home pregnancy testing modestly advances detection but substantially increases false negatives and detection of very early pregnancy losses, according to a recent study.

Study author Oskari Heikinheimo explains how patients should approach earlier surveillance, fertility options, and pregnancy considerations and risks for women with endometriosis.

A Finnish registry study found that individuals with endometriosis have significantly higher risks of miscarriage and ectopic pregnancy and a lower lifetime incidence of pregnancy.

The updated Committee Statement reaffirmed the safety and benefits of influenza, COVID-19, Tdap, and RSV vaccines during pregnancy while addressing misinformation and disparities.

An institution-wide policy allowing elective induction at 39 weeks was linked to lower cesarean delivery and NICU admission rates.

The findings underscore the need for more rigorous and diverse clinical studies evaluating digital interventions.