Pregnancy and Birth

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Research has shown that glucocorticoid administration has a significant beneficial effect for preterm births, as it decreases the incidence of respiratory distress syndrome in infants delivered between 24 weeks and 34 weeks gestation, reduces the incidence of intraventricular hemorrhage, improves circulatory stability in premature infants, reduces the need for oxygen and ventilatory support, and reduces overall neonatal mortality.

Although uterine leiomyomas are benign tumors, its symptoms, including anemia, excessive vaginal bleeding, pelvic pain, pressure-related bowel and bladder dysfunction, recurrent miscarriage and preterm labor, can severely negatively impact patients’ quality of life. Since uterine leiomyomas are three to four times more common in African-American patients, and since African-American women have 10 times higher incidence of hypovitaminosis D than white women, researchers sought to explore the impact of vitamin D3 on uterine leiomyomas.