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Cranberry-containing products may be more than just a folk remedy for urinary tract infections (UTIs). A systematic review and meta-analysis published in the Archives of Internal Medicine concludes that cranberry-containing products offer women protection against UTIs, particularly those prone to recurrent infections.

In this chapter, Dr. Owen reviews the diagnosis or cervical insufficiency; patient selection for history-indicated (prophylactic), physical examination-indicated (Emergent), and ultrasound-indicated (urgent) cerclage; placement and removal of cerclagel and adjunctive therapies.

The United States Food and Drug Administration (FDA), under its priority review program, recently approved PerjetaTM (pertuzumab), a HER2/neu receptor antagonist indicated in combination with HerceptinR (trastuzumab), another HER2 therapy, and docetaxel for treatment of HER2-positive metastatic breast cancer (BCa) in women who have not received prior anti-HER2 therapy or chemotherapy for metastatic disease.

Analysis by the United States Food and Drug Administration (FDA) of compounded 17α-hydroxyprogesterone caproate (17P) shows the samples meet the potency and total purity standards for Makena, the branded version of the drug. Testing was done on 16 samples of bulk 17P active pharmaceutical ingredients (API) in response to questions from K-V Pharmaceuticals, Makena’s sponsor, about potency and purity of the compounded product.