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A detailed look at the design and outcomes of the monkey trial on tibolone, by Drs. Tom Clarkson and Leon Speroff. Available only online in conjunction with the authors' article, "Is tibolone a viable alternative to HT?" in our August 2003 issue.

A large body of research suggests that tumors in hormone users are better-differentiated and of lower grade and stage, with better outcomes. The contrary findings from WHI may reflect the older age of the participants and a need to discontinue HT 2 weeks before mammography in women aged 65 and older with dense breasts.

Clinical experience in humans in many countries and studies in monkeys say yes. Tibolone offers the symptom relief and bone benefits of CEE with endometrial safety--without stimulating breast tissue or increasing the risk of CAD.

Before choosing the appropriate surgical procedure, a two-pronged approach--transvaginal ultrasonography and CA-125 assessment--is the best way to determine the benign or malignant nature of an ovarian mass.

A cancer diagnosis no longer necessarily ends a woman's life--or her future fertility. Experts offer an update on two ways of salvaging potential fertility.

Mounting evidence suggests that a chronic oral infection may lead to an immune reaction that either triggers premature parturition or contributes to its onset.

Drug therapy isn't recommended for all women with osteopenia, a precursor to osteoporosis. Clinicians need to identify, early on, the patients with low bone mass at additional risk for future osteoporotic fractures.

Patients need an individualized approach, says this expert in pelvic reconstructive surgery. Many factors determine whether minimally invasive versus invasive surgery, or abdominal versus vaginal routes of repair are best.

A many as 20% of specimens from liquid-based cytology may lack a TZ component. The author examines the evidence on whether that should be of concern to clinicians and reveals two easy steps that can help you obtain more TZ in Pap specimens.

When should a patient who menstruates normally be diagnosed as having polycystic ovary syndrome, and what clinical differences exist between these somewhat atypical women and those with classic PCOS?

Should women be permitted to request a C/S? Physicians on both sides of the debate offer cogent arguments. What they say can help your own approach.

Therapeutic amenorrhea is not always easy to initiate or to maintain. But anticipating prolonged, heavy bleeding in patients with certain medical problems--and managing it prophylactically--is far better than trying to stop potentially life-threatening bleeding once it's begun.

Will the cutting-edge technology of protein profiling revolutionize medicine in general and early ovarian cancer detection in particular?

Rational decision-making and raging adolescent hormones do sound like strange bedfellows. But research reveals some ways ob/gyns can help teens make wiser choices--and grow into healthy sexual adults.

A critical look at black cohosh, soy, chasteberry, and related supplements finds some evidence to support their use, but randomized large-scale clinical trials to definitively prove their worth are sorely needed.

Clearly, that's true for high-risk gestations in general. But while the use of Doppler U/S for managing IUGR pregnancies is creating much excitement, it does have limitations.

Consider the pros and cons before adding cosmetic procedures, advises this article from Medical Economics OB/GYN edition.

A diagnostic work up holds the challenge of ruling out uterine malignancy and hyperplasia, as well as pinpointing the noncancerous cause of the bleeding. An expert in the field outlines the most appropriate assessment tools to help accomplish these goals.

Rational decision-making and raging adolescent hormones do sound like strange bedfellows. But research reveals some ways ob/gyns can help teens make wiser choices--and grow into healthy sexual adults.

Thromboembolic complications are common after gynecologic surgery. All too often, DVT is discovered on autopsy. The authors offer a practical evidence-based perspective on prophylaxis with external pneumatic compression and LMWH.

Although nearly 40% of women have metabolic syndrome and the incidence is rising, the condition remains underdiagnosed. Clinicians who treat postmenopausal women should increase their awareness of the metabolic derangements associated with the syndrome and consider them when weighing hormone therapy options.