Menopause is the time in a woman's life when the ovaries stop producing estrogen. Menopause is usually recognized by the cessation of menstrual periods. Other symptoms of menopause include flashes, mood changes, difficulty sleeping, and vaginal dryness. If a woman is not menstruating because she has had a hysterectomy or endometrial ablation, other symptoms of menopause often alert her that menopause is starting.
A small study presented at the 2014 ACOG Annual Clinical Meeting suggests that a selective estrogen receptor modulator (SERM) plus estrogen may have promise in treatment of perimenopausal symptoms. According to Japanese researchers, the combination—known as tissue-selective estrogen complex—improved climacteric symptoms and bone resorption markers without severe side effects.