Opinion|Videos|December 15, 2025

Integrating Evidence to Enhance Treatment Approaches for VMS and Sleep

Fiona C. Baker, PhD, summarizes the most clinically relevant takeaways from NIRVANA and explores how these findings may shape future treatment decisions and guideline conversations.

This final episode highlights how NIRVANA’s combination of objective and subjective data demonstrates meaningful reductions in wakefulness, awakenings, and arousals, complementing earlier OASIS results and advancing the science of menopause-related sleep research. These findings may influence future guideline considerations and enrich provider–patient discussions about addressing nighttime symptoms more proactively. The conversation closes by noting that with FDA approval and a growing evidence base, clinicians now have a more robust and targeted option for treating both vasomotor symptoms and sleep disturbance.

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