Breast Health

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Despite earlier observational studies, bisphosphonate treatment for 3 to 4 years appears not to decrease the risk of invasive postmenopausal breast cancer, according to a new study in JAMA Internal Medicine.

Mutations in the PALB2 gene may be associated with a significant increase in the risk of breast cancer, according to a recent study in The New England Journal of Medicine. PALB2 binds to BRCA2-a gene that confers increased lifetime risk of developing breast or ovarian cancer-and likely permits its stable nuclear localization and accumulation.

A reduced-carbohydrate diet may reduce breast cancer recurrence in women whose tumor tissue is positive for insulin-like growth factor-I (IGF1) receptor, according to a new study in Cancer Epidemiology Biomarkers & Prevention.

Substituting one serving per day of legumes for one serving per day of red meat may help lower a woman’s risk of breast cancer, according to results of a multicenter study based on data from the Nurses’ Health Study II. The findings, published in BMJ, represent 20 years of follow up on a questionnaire on diet.

A new analysis of data from a nationwide hospital-based dataset shows that black women have higher odds of being diagnosed with triple-negative breast cancer-a subtype associated with poorer prognosis-than do white women, regardless of socioeconomic status (SES). The report was published in the June issue of Breast Cancer Research and Treatment.