October 17th 2023
This lecture, presented by Holly J. Pederson, MD, at The Menopause Society 2023 Annual Meeting, looked at combined oral contraceptives in BRCA carriers and other high-risk patients, and hormone therapy in postmenopausal gene carriers as well as other high-risk women.
23rd Annual International Congress on the Future of Breast Cancer® East
July 19-20, 2024
Register Now!
Patient, Provider, and Caregiver Connection™: Incorporating the Patient Journey into HS Diagnosis and Management Practices
View More
Patient, Provider, & Caregiver Connection: Individualizing Care in Multiple Sclerosis – Understanding Patient Challenges and the Role of Innovative Treatment
View More
Expert Illustrations & Commentaries™: Targeting Immune Cells to Treat Multiple Sclerosis
View More
15th Annual International Symposium on Ovarian Cancer and Other Gynecologic Malignancies™
May 11, 2024
View More
Community Practice Connections™: 14th Annual International Symposium on Ovarian Cancer and Other Gynecologic Malignancies
View More
4th Annual International Congress on the Future of Women’s Health™
View More
Younger Age at Breast Cancer Diagnosis Associated With Subsequent Primary Cancer
August 29th 2011Are younger women with breast cancer more likely to develop another primary cancer later in life as compared to their older counterparts? According to some experts, younger women may have more unfavorable tumor characteristics. Others hypothesize this increase is observed because younger women can be observed for longer periods. To better understand this phenomenon, Dr Lene Mellemkjaer, senior researcher at the Institute of Cancer Epidemiology of the Danish Cancer Society in Copenhagen, Denmark, and colleagues conducted a study of 304,703 women who received a diagnosis of breast cancer between 1943 and 2006 according to registries in Denmark, Norway, and Finland.
Read More
Poll: Do You Offer Annual Mammography Screening to Women 40 Years and Older?
August 22nd 2011A new recommendation by The American College of Obstetricians and Gynecologists urges physicians to offer mammography screening annually to women beginning at age 40 years. The College previously recommended that women aged 40 years receive mammograms every 1 to 2 years and women aged 50 years have mammograms annually.
Read More
Meta-Analysis Furthers Evidence of Tamoxifen’s Efficacy
August 22nd 2011Advances in the treatment for breast cancer have allowed for better outcomes and decreased mortality rates. Tamoxifen, the oldest and most frequently prescribed selective estrogen receptor modulator approved by the US Food and Drug Administration, has shown great efficacy, and studies of tamoxifen treatment lasting 5 years now have follow-up efficacy data that go past one decade. To better understand the evidence, the Early Breast Cancer Trialists’ Collaborative Group (EBCTCG) conducted a meta-analysis of 20 trials to ascertain the protective effects of tamoxifen in reducing recurrence and death ratios.
Read More
Offer Annual Mammograms to Women 40 Years and Older, Says ACOG
August 16th 2011Mammography screening should be offered annually to women beginning at age 40 years, according to a new recommendation by The American College of Obstetricians and Gynecologists (The College).1 This change was brought about by the high incidence of breast cancer in the United States. Early detection of breast cancer has the potential to reduce the number of breast cancer–related deaths. The College previously recommended that women aged 40 years receive mammograms every 1 to 2 years and women aged 50 years have mammograms annually.
Read More
European Study Sheds Light on Impact of Mammography Screening on Breast Cancer Morbidity
August 7th 2011Breast cancer mortality appears to be decreasing not only in the United States but internationally as well. While mammography and screening supporters point to its efficacy as the main reason for this decrease, there is no definitive answer. With that in mind, Dr Philippe Autier, research director at the International Prevention Research Institute in Lyon, France, and colleagues sought to compare the trends in breast cancer mortality and the relative screening policies among 3 pairs of neighboring European countries.
Read More
Novel Multistatic Adaptive Microwave Imaging Methods for Early Breast Cancer Detection
August 3rd 2011Multistatic adaptive microwave imaging (MAMI) methods are presented and compared for early breast cancer detection. Due to the significant contrast between the dielectric properties of normal and malignant breast tissues, developing microwave imaging techniques for early breast cancer detection has attracted much interest lately.
Read More
Radiation Therapy Planning with Photons and Protons for Early and Advanced Breast Cancer
August 3rd 2011Postoperative radiation therapy substantially decreases local relapse and moderately reduces breast cancer mortality, but can be associated with increased late mortality due to cardiovascular morbidity and secondary malignancies.
Read More
Genotypes and Haplotypes of the Methyl-CpG-Binding Domain 2 Modify Breast Cancer Risk
August 3rd 2011MBD2, the gene encoding methyl-CpG-binding domain (MBD)2, is a major methylation related gene and functions as a transcriptional repressor that can specifically bind to the methylated regions of other genes. MBD2 may also mediate gene activation because of its potential DNA demethylase activity.
Read More
New Studies Indicate Age Is Important in Hormone Therapy Use
August 3rd 2011Five years ago this summer the National Institutes of Health’s stopped early a major portion of the Women’s Health Initiative (WHI), a large and ambitious study to address the most common causes of death, disability and impaired quality of life in postmenopausal women.
Read More
IGFBP3 mRNA Expression in Benign and Malignant Breast Tumors
August 3rd 2011Most previous studies have focused on evaluating the association between circulating insulin-like growth factor binding protein 3 (IGFBP-3) levels and breast cancer risk. Emerging evidence over the past few years suggests that IGFBP-3 may act directly on mammary epithelial cells.
Read More
Hormone-related Risk Factors for Breast Cancer in Women Under Age 50 Years
August 3rd 2011It has been suggested that hormonal risk factors act predominantly on estrogen receptor and progesterone receptor (ER/PR)-positive breast cancers. However, the data have been inconsistent, especially in younger women.
Read More
Gene Expression Profiles in Core Biopsies and Corresponding Surgical Breast Cancer Samples
August 3rd 2011Gene expression profiling has been successfully used to classify breast cancer into clinically distinct subtypes, and to predict the risk of recurrence and treatment response. The aim of this study was to investigate whether the gene expression profile (GEP) detected in a core biopsy (CB) is representative for the entire tumor, since CB is an important tool in breast cancer diagnosis.
Read More
Molecular Structure of Cancer-Related Proteins Identified
August 3rd 2011Research published in this week's issue of Nature describes the molecular structure of two cancer-related proteins binding to one another. Scientists identified the biochemical and signaling properties of these molecules using a process called X-ray crystallography.
Read More
New role for tamoxifen as fertility drug for breast cancer patients?
August 3rd 2011In a study published today in Europe's leading reproductive medicine journal Human Reproduction1, researchers from New York's Cornell University report the first IVF pregnancy to result from the use of tamoxifen as an ovarian stimulant.
Read More
Special Report: HER2 and Trastuzumab in Breast Cancer
August 3rd 2011The recognition and description of tumor growth control factors, together with the development of interventions that modulate their biologic activity, represent a major focus for current cancer research, which already has changed the practice of clinical oncology.
Read More
What Men Can Do: Helping Women Cope with Breast Cancer
August 3rd 2011Breast cancer is traumatic not only for the women who develop it, but also for the men in their lives. I know. In 1991, my wife was diagnosed, and I found myself along for an unpleasant ride as she had surgery, two months of daily radiation, and six months of biweekly chemotherapy, not to mention the emotional upheaval the disease engenders.
Read More
Immune Responses to Human MUC1 Mucin: Relevance for Cancer Immunotherapy
August 3rd 2011Human MUC1 mucin, a membrane-bound glycoprotein, is a major component of the ductal cell surface of normal glandular cells. MUC1 is overexpressed and aberrantly glycosylated in carcinoma cells. The role MUC1 plays in cancer progression represents two sides of one coin.
Read More
Minimizing Breast Pain: Recommendations
August 3rd 2011Sore breasts can signal the onset of PMS -- that 'ouch' feeling tells some women they're premenstrual more reliably than a calendar. Cyclical breast soreness shouldn't cause concern, according to Women's Health America. However, breast pain doesn't have to be tolerated. Here's how to minimize discomfort, and how to recognize cautionary signs that should send you to your doctor.
Read More
Tumor Marker Testing Fact Sheet
August 3rd 2011Tumor marker tests include a variety of tests for cancer that can be performed on cells of a tissue sample from a newly biopsied or stored tumor. Tumor marker testing provides the patient and oncologist with vital information about the tumor at the cellular level, expanding traditional pathology reports that are based on tumor size, appearance and staging of the disease.
Read More
Breast Cancer Awareness: Is the Message Getting Blurred?
August 3rd 2011At 30,000 feet, breast cancer awareness is probably not the first thing on an airline passenger’s mind. But Delta Airlines is trying to change all that. Delta’s “Force for Global Good” is offering $2 glasses of pink lemonade to customers and donating all proceeds to The Breast Cancer Research Foundation (BCRF).
Read More
Barbara's Reflections My Journey Living With Breast Cancer
August 3rd 2011This month is National Breast Cancer Awareness Month and so I feel it's an appropriate time to Reflect on my last eighteen months going down that road. I will try not to make this a sad trip but instead a hopeful one for all of us either with the disease or with loved one's going through this journey.
Read More
Barbara's Reflections: Out on a limb, hanging by my fingertips!
August 3rd 2011This week on the Women's Forum there have been two posts that have "touched home" for me. I must share with you that I was hesitant at first to answer them. Why, you are probably asking... Well they are Both subjects that I am completely familiar with and yet felt reluctant to open-up about on the forum.
Read More