Menopause

Steroid hormones have a typical chemical structure. Their mechanism of action is through binding to a specific receptor which in the nucleus of the cell will induce effects at the genomic level.

Hormonal changes associated with menopause do not increase a woman’s risk for heart disease and heart disease mortality, according to new research published in BMJ. The work of Dr Dhananjay Vaidya, assistant professor of medicine at John Hopkins School of Medicine, and colleagues contradict the previously hypothesis that heart disease and heart attacks rise dramatically after menopause.

A new study provides a real-world snapshot of risks associated with venous thromboembolism in women receiving hormone replacement therapy, demonstrating that women who use an estradiol transdermal system may have less risk of developing thromboembolism than their counterparts who receive oral estrogen-only hormone therapy agents.

Pfizer Inc. reports that it has received a "complete response letter" from the Food and Drug Administration (FDA) denying its application to approve desvenlafaxine (Pristiq) for moderate to severe vasomotor symptoms of menopause such as hot flashes.

A recent study on sleep disturbances in menopause shows a direct connection to the use of hormone therapy. Specifically, when women stop taking hormone therapy they experienced greater periods of poor sleep, waking up during the night, difficulty falling asleep, waking up to early and not feeling rested.

According to results from a new study, a popular herbal remedy may come to the rescue of women suffering from postmenopausal sleep disturbances. About half of postmenopausal women experience some degree of sleep disturbance, which in turn impacts their quality of life.

Cessation of hormone therapy in menopausal women may result in sleep disturbances, according to a new study in Menopause. Since the hormone therapy has been associated with the alleviation of sleep problems in women experiencing menopausal symptoms, Dr Sarah E Tom, Interdisciplinary Women’s Health Research (IWHR) Scholar at the University of Texas Medical School, and colleagues sought to determine the resulting sleep effects during cessation of hormone therapy.

With the rate of diabetes and prediabetes/glucose intolerance increasing, it is imperative for clinicians to help reduce the risk of their patients developing full-blown diabetes as well as to help patients manage the illness.

Positive Association Between Mammographic Breast Density and Bone Mineral Density in thePostmenopausal Estrogen/Progestin Interventions Study