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Postoperative radiation therapy substantially decreases local relapse and moderately reduces breast cancer mortality, but can be associated with increased late mortality due to cardiovascular morbidity and secondary malignancies.

Positive Association Between Mammographic Breast Density and Bone Mineral Density in thePostmenopausal Estrogen/Progestin Interventions Study

Transcriptional Changes Associated with Breast Cancer Occur as Normal Human Mammary Epithelial CellsOvercome Senescence Barriers and Become Immortalized

It has been suggested that hormonal risk factors act predominantly on estrogen receptor and progesterone receptor (ER/PR)-positive breast cancers. However, the data have been inconsistent, especially in younger women.

In a study published today in Europe's leading reproductive medicine journal Human Reproduction1, researchers from New York's Cornell University report the first IVF pregnancy to result from the use of tamoxifen as an ovarian stimulant.

Breast cancer is traumatic not only for the women who develop it, but also for the men in their lives. I know. In 1991, my wife was diagnosed, and I found myself along for an unpleasant ride as she had surgery, two months of daily radiation, and six months of biweekly chemotherapy, not to mention the emotional upheaval the disease engenders.

Human MUC1 mucin, a membrane-bound glycoprotein, is a major component of the ductal cell surface of normal glandular cells. MUC1 is overexpressed and aberrantly glycosylated in carcinoma cells. The role MUC1 plays in cancer progression represents two sides of one coin.

Sore breasts can signal the onset of PMS -- that 'ouch' feeling tells some women they're premenstrual more reliably than a calendar. Cyclical breast soreness shouldn't cause concern, according to Women's Health America. However, breast pain doesn't have to be tolerated. Here's how to minimize discomfort, and how to recognize cautionary signs that should send you to your doctor.

Breast Cancer and Breast Disease

This month is National Breast Cancer Awareness Month and so I feel it's an appropriate time to Reflect on my last eighteen months going down that road. I will try not to make this a sad trip but instead a hopeful one for all of us either with the disease or with loved one's going through this journey.

This week on the Women's Forum there have been two posts that have "touched home" for me. I must share with you that I was hesitant at first to answer them. Why, you are probably asking... Well they are Both subjects that I am completely familiar with and yet felt reluctant to open-up about on the forum.

Janet George is a mother of three, grandmother of seven, and a breast cancer survivor. Her story began after a routine mammogram. Janet's mother died of breast cancer, so regular mammograms have always been part of her healthcare. Janet was notified that a small tumor had been found during a routine mammogram, and her cancer was diagnosed after a wire localization biopsy.

Disclosure Declaration •Grant Support –National Institutes of Health, Ortho-McNeil Pharmaceutical, Inc, Pharmacia Corp., Berlex Laboratories, Proctor and Gamble •Honoraria and consultation fees –Ortho-McNeil Pharmaceutical, Inc., Berlex Laboratories, Pharmacia Corp., TAP Pharmaceuticals, Eli Lilly and Co. •Participation in company sponsored speakers’ bureau –Ortho-McNeil Pharmaceutical, Inc., Berlex Laboratories, Pharmacia Corp., Merck Pharmaceuticals.

Educational tutorial on endometriosis.

ORAL CONTRACEPTIVES: . Objectives . Know the risks, benefits and side effects of oral contraceptives . Utilize basic concepts in OC prescribing . Know how to modify regiments to manage side effects .Objectives .Know the risks, benefits and side effects of oral contraceptives .Utilize basic concepts in OC prescribing .Know how to modify regiments to manage side effects

Extended Use of Combined Oral Contraceptive PillsDr Hamed EllakwaAssociate Professor of Obsterics and GynecologyMenoufiya University, Egyptdrhamedellakwa@yahoo.com

Endometriosis-An Overview Prof. Dr. Mohammad A. Emam Prof. of Obstetrics and Gynecology Mansoura Faculty of Medicine Mansoura Integrated Fertility Center (MIFC) EgyptEmam MA, EGYPT, 2003

INFLAMMATORY BREAST CANCER (IBC) is an advanced and accelerated form of breast cancer automatically rated as Stage IIIb that usually is not detected by mammograms or ultrasounds. It requires immediate aggressive treatment with chemotherapy prior to surgery and is treated differently than more common types of breast cancer.

Two new types of antiprogestins that can suppress menstruation and could end the monthly misery many women suffer have passed their first tests in animals, scientists report today (Friday 27 July) in Europe's leading reproductive medicine journal, Human Reproduction.

Talk about breast cancer and naturally, people think of the disease that is the number one cancer among women. But the truth is that breast cancer is on the rise among both women and men, and researchers think the national obesity crisis may be to blame.

The HERS trial was the first study to put a damper on enthusiasm for hormone replacement therapy (HRT) as a preventive therapy for heart disease. A second trial called ERA (Estrogen Replacement and Atheriosclerosis trial), reported at the 49th Annual Meeting of the American College of Cardiology, held in Anaheim, California, March 12–15, 2000, provides additional evidence that HRT does not prevent heart disease.

Hysterectomy is one of the most common abdominal surgical procedures performed in women today with 600,000 hysterectomies in the USA annually, one in three women undergoing hysterectomy, and 6–20% in European countries.

The optimal surgical approach to treatment of stress urinary incontinence (SUI) in women continues to be a topic of controversy. This debate is fueled, in part, by the difficulty in comparing data on the different surgical procedures due to variations in patient selection, diagnostic methods, techniques, outcome criteria, and length of follow-up.

Interview with Steve Fleischman